Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Adam17 | Arl11 | ENSMUSP00000099087 | ENSMUSP00000153531 | Disintegrin and metalloproteinase domain-containing protein 17; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Plays a role in the proteolytic processing of ACE2 (By similarity). Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of [...] | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | 0.529 |
| Arl11 | Adam17 | ENSMUSP00000153531 | ENSMUSP00000099087 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | Disintegrin and metalloproteinase domain-containing protein 17; Cleaves the membrane-bound precursor of TNF-alpha to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Plays a role in the proteolytic processing of ACE2 (By similarity). Responsible for the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin 1 receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1 and the amyloid precursor protein. Acts as an activator of [...] | 0.529 |
| Arl11 | Arl16 | ENSMUSP00000153531 | ENSMUSP00000076188 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | ADP-ribosylation factor-like 16. | 0.566 |
| Arl11 | Cdadc1 | ENSMUSP00000153531 | ENSMUSP00000153357 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis. | 0.538 |
| Arl11 | Cnbd1 | ENSMUSP00000153531 | ENSMUSP00000121576 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | Cyclic nucleotide-binding domain-containing 1. | 0.538 |
| Arl11 | Gbf1 | ENSMUSP00000153531 | ENSMUSP00000026254 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | Golgi-specific brefeldin A-resistance factor 1. | 0.489 |
| Arl11 | Hif1an | ENSMUSP00000153531 | ENSMUSP00000035326 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | Hypoxia-inducible factor 1-alpha inhibitor; Hydroxylates HIF-1 alpha at 'Asn-799' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins. Also hydroxylat [...] | 0.714 |
| Arl11 | Itsn1 | ENSMUSP00000153531 | ENSMUSP00000109635 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (By similarity). Plays a role in the assembly and maturation of clathrin- coated vesicles (By similarity). Recruits FCHSD2 to clathrin-coated pits (By similarity). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin rece [...] | 0.593 |
| Arl11 | Itsn2 | ENSMUSP00000153531 | ENSMUSP00000052758 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | Intersectin-2; Adapter protein that may provide indirect link between the endocytic membrane traffic and the actin assembly machinery. May regulate the formation of clathrin-coated vesicles (CCPs). Seems to be involved in CCPs maturation including invagination or budding. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR). Plays a role in dendrite formation by melanocytes. | 0.629 |
| Arl11 | Plekhg3 | ENSMUSP00000153531 | ENSMUSP00000074729 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | Pleckstrin homology domain-containing family G member 3. | 0.568 |
| Arl11 | Rnf149 | ENSMUSP00000153531 | ENSMUSP00000050388 | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | E3 ubiquitin-protein ligase RNF149; E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation. | 0.519 |
| Arl16 | Arl11 | ENSMUSP00000076188 | ENSMUSP00000153531 | ADP-ribosylation factor-like 16. | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | 0.566 |
| Cdadc1 | Arl11 | ENSMUSP00000153357 | ENSMUSP00000153531 | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis. | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | 0.538 |
| Cdadc1 | Cnbd1 | ENSMUSP00000153357 | ENSMUSP00000121576 | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis. | Cyclic nucleotide-binding domain-containing 1. | 0.519 |
| Cdadc1 | Rnf149 | ENSMUSP00000153357 | ENSMUSP00000050388 | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis. | E3 ubiquitin-protein ligase RNF149; E3 ubiquitin-protein ligase. Ubiquitinates BRAF, inducing its proteasomal degradation. | 0.533 |
| Cnbd1 | Arl11 | ENSMUSP00000121576 | ENSMUSP00000153531 | Cyclic nucleotide-binding domain-containing 1. | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | 0.538 |
| Cnbd1 | Cdadc1 | ENSMUSP00000121576 | ENSMUSP00000153357 | Cyclic nucleotide-binding domain-containing 1. | Cytidine and dCMP deaminase domain-containing protein 1; May play an important role in testicular development and spermatogenesis. | 0.519 |
| Gbf1 | Arl11 | ENSMUSP00000026254 | ENSMUSP00000153531 | Golgi-specific brefeldin A-resistance factor 1. | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | 0.489 |
| Hif1an | Arl11 | ENSMUSP00000035326 | ENSMUSP00000153531 | Hypoxia-inducible factor 1-alpha inhibitor; Hydroxylates HIF-1 alpha at 'Asn-799' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coactivators including Cbp/p300-interacting transactivator. Involved in transcriptional repression through interaction with HIF1A, VHL and histone deacetylases. Hydroxylates specific Asn residues within ankyrin repeat domains (ARD) of NFKB1, NFKBIA, NOTCH1, ASB4, PPP1R12A and several other ARD-containing proteins. Also hydroxylat [...] | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | 0.714 |
| Itsn1 | Arl11 | ENSMUSP00000109635 | ENSMUSP00000153531 | Intersectin-1; Adapter protein that provides a link between the endocytic membrane traffic and the actin assembly machinery. Acts as guanine nucleotide exchange factor (GEF) for CDC42, and thereby stimulates actin nucleation mediated by WASL and the ARP2/3 complex (By similarity). Plays a role in the assembly and maturation of clathrin- coated vesicles (By similarity). Recruits FCHSD2 to clathrin-coated pits (By similarity). Involved in endocytosis of activated EGFR, and probably also other growth factor receptors. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin rece [...] | ADP-ribosylation factor-like protein 11; May play a role in apoptosis. May act as a tumor suppressor (By similarity). | 0.593 |
page 1 of 2