Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Abcd4 | Sall3 | ENSMUSP00000021666 | ENSMUSP00000056967 | ATP-binding cassette sub-family D member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm (By similarity). | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | 0.489 |
| Cdh19 | Sall3 | ENSMUSP00000092210 | ENSMUSP00000056967 | Cadherin 19, type 2; Cadherins are calcium-dependent cell adhesion proteins. | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | 0.470 |
| Coq2 | Sall3 | ENSMUSP00000031262 | ENSMUSP00000056967 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | 0.461 |
| Hoxd12 | Sall3 | ENSMUSP00000001878 | ENSMUSP00000056967 | Homeobox protein Hox-D12; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | 0.474 |
| Lgals4 | Sall3 | ENSMUSP00000066461 | ENSMUSP00000056967 | Galectin-4; Galectin that binds lactose and a related range of sugars. | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | 0.520 |
| Mast1 | Sall3 | ENSMUSP00000105363 | ENSMUSP00000056967 | Microtubule-associated serine/threonine-protein kinase 1; Microtubule-associated protein essential for correct brain development. Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | 0.693 |
| Nanog | Pou5f1 | ENSMUSP00000012540 | ENSMUSP00000025271 | Homeobox protein NANOG; Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'- TAAT[GT][GT [...] | POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Belongs to the POU transcription factor family. Class-5 subfamily. | 0.999 |
| Nanog | Sall3 | ENSMUSP00000012540 | ENSMUSP00000056967 | Homeobox protein NANOG; Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'- TAAT[GT][GT [...] | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | 0.562 |
| Nanog | Sox2 | ENSMUSP00000012540 | ENSMUSP00000096755 | Homeobox protein NANOG; Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'- TAAT[GT][GT [...] | Transcription factor SOX-2; Transcription factor that forms a trimeric complex with POU5F1 (OCT3/4) on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Binds to the proximal enhancer region of NANOG. Critical for early embryogenesis and for embryonic stem cell pluripotency (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarit [...] | 0.998 |
| Nox3 | Sall3 | ENSMUSP00000111466 | ENSMUSP00000056967 | NADPH oxidase 3; NADPH oxidase which constitutively produces superoxide upon formation of a complex with CYBA/p22phox. Plays a role in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity. | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | 0.568 |
| Pou5f1 | Nanog | ENSMUSP00000025271 | ENSMUSP00000012540 | POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Belongs to the POU transcription factor family. Class-5 subfamily. | Homeobox protein NANOG; Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'- TAAT[GT][GT [...] | 0.999 |
| Pou5f1 | Sall3 | ENSMUSP00000025271 | ENSMUSP00000056967 | POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Belongs to the POU transcription factor family. Class-5 subfamily. | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | 0.615 |
| Pou5f1 | Sox2 | ENSMUSP00000025271 | ENSMUSP00000096755 | POU domain, class 5, transcription factor 1; Transcription factor that binds to the octamer motif (5'- ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. Belongs to the POU transcription factor family. Class-5 subfamily. | Transcription factor SOX-2; Transcription factor that forms a trimeric complex with POU5F1 (OCT3/4) on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Binds to the proximal enhancer region of NANOG. Critical for early embryogenesis and for embryonic stem cell pluripotency (By similarity). Downstream SRRT target that mediates the promotion of neural stem cell self-renewal. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarit [...] | 0.999 |
| Sall3 | Abcd4 | ENSMUSP00000056967 | ENSMUSP00000021666 | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | ATP-binding cassette sub-family D member 4; May be involved in intracellular processing of vitamin B12 (cobalamin). Could play a role in the lysosomal release of vitamin B12 into the cytoplasm (By similarity). | 0.489 |
| Sall3 | Cdh19 | ENSMUSP00000056967 | ENSMUSP00000092210 | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | Cadherin 19, type 2; Cadherins are calcium-dependent cell adhesion proteins. | 0.470 |
| Sall3 | Coq2 | ENSMUSP00000056967 | ENSMUSP00000031262 | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.461 |
| Sall3 | Hoxd12 | ENSMUSP00000056967 | ENSMUSP00000001878 | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | Homeobox protein Hox-D12; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. | 0.474 |
| Sall3 | Lgals4 | ENSMUSP00000056967 | ENSMUSP00000066461 | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | Galectin-4; Galectin that binds lactose and a related range of sugars. | 0.520 |
| Sall3 | Mast1 | ENSMUSP00000056967 | ENSMUSP00000105363 | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | Microtubule-associated serine/threonine-protein kinase 1; Microtubule-associated protein essential for correct brain development. Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. | 0.693 |
| Sall3 | Nanog | ENSMUSP00000056967 | ENSMUSP00000012540 | Sal-like protein 3; Probable transcription factor; Belongs to the sal C2H2-type zinc-finger protein family. | Homeobox protein NANOG; Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'- TAAT[GT][GT [...] | 0.562 |
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