node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Adgrl1 | Lrrn4 | ENSMUSP00000118452 | ENSMUSP00000057005 | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity); Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | 0.526 |
Adgrl2 | Lrrn4 | ENSMUSP00000143626 | ENSMUSP00000057005 | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | 0.526 |
Adgrl3 | Lrrn4 | ENSMUSP00000072336 | ENSMUSP00000057005 | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | 0.526 |
Gpm6a | Lrrn4 | ENSMUSP00000033915 | ENSMUSP00000057005 | Neuronal membrane glycoprotein M6-a; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. Gpm6a-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. Conflictingly, reports that induced cellular protrusions are simple membrane-wrapped tubules without actin or tubulin-based cytoskeletons and with Gpm6a gliding along membrane edges indicative for a func [...] | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | 0.515 |
Gpm6a | Msln | ENSMUSP00000033915 | ENSMUSP00000158357 | Neuronal membrane glycoprotein M6-a; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. Gpm6a-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. Conflictingly, reports that induced cellular protrusions are simple membrane-wrapped tubules without actin or tubulin-based cytoskeletons and with Gpm6a gliding along membrane edges indicative for a func [...] | Megakaryocyte-potentiating factor; Membrane-anchored forms may play a role in cellular adhesion. Belongs to the mesothelin family. | 0.448 |
Gpm6a | Nkain4 | ENSMUSP00000033915 | ENSMUSP00000099342 | Neuronal membrane glycoprotein M6-a; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. Gpm6a-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. Conflictingly, reports that induced cellular protrusions are simple membrane-wrapped tubules without actin or tubulin-based cytoskeletons and with Gpm6a gliding along membrane edges indicative for a func [...] | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4; Belongs to the NKAIN family. | 0.471 |
Gpm6a | Upk1b | ENSMUSP00000033915 | ENSMUSP00000052469 | Neuronal membrane glycoprotein M6-a; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. Gpm6a-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. Conflictingly, reports that induced cellular protrusions are simple membrane-wrapped tubules without actin or tubulin-based cytoskeletons and with Gpm6a gliding along membrane edges indicative for a func [...] | Uroplakin-1b; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity). | 0.649 |
Gpm6a | Upk3b | ENSMUSP00000033915 | ENSMUSP00000062312 | Neuronal membrane glycoprotein M6-a; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. Gpm6a-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. Conflictingly, reports that induced cellular protrusions are simple membrane-wrapped tubules without actin or tubulin-based cytoskeletons and with Gpm6a gliding along membrane edges indicative for a func [...] | Uroplakin-3b; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity). | 0.635 |
Higd1b | Lrrn4 | ENSMUSP00000021302 | ENSMUSP00000057005 | HIG1 domain family member 1B. | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | 0.446 |
Lrrn4 | Adgrl1 | ENSMUSP00000057005 | ENSMUSP00000118452 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Adhesion G protein-coupled receptor L1; Calcium-independent receptor of high affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor for TENM2 that mediates heterophilic synaptic cell-cell contact and postsynaptic specialization. Receptor probably implicated in the regulation of exocytosis (By similarity); Belongs to the G-protein coupled receptor 2 family. Adhesion G-protein coupled receptor (ADGR) subfamily. | 0.526 |
Lrrn4 | Adgrl2 | ENSMUSP00000057005 | ENSMUSP00000143626 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Adhesion G protein-coupled receptor L2; Calcium-independent receptor of low affinity for alpha- latrotoxin, an excitatory neurotoxin present in black widow spider venom which triggers massive exocytosis from neurons and neuroendocrine cells. Receptor probably implicated in the regulation of exocytosis. | 0.526 |
Lrrn4 | Adgrl3 | ENSMUSP00000057005 | ENSMUSP00000072336 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Adhesion G protein-coupled receptor L3; Plays a role in cell-cell adhesion and neuron guidance via its interactions with FLRT2 and FLRT3 that are expressed at the surface of adjacent cells. Plays a role in the development of glutamatergic synapses in the cortex. Important in determining the connectivity rates between the principal neurons in the cortex. | 0.526 |
Lrrn4 | Gpm6a | ENSMUSP00000057005 | ENSMUSP00000033915 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Neuronal membrane glycoprotein M6-a; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. Gpm6a-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. Conflictingly, reports that induced cellular protrusions are simple membrane-wrapped tubules without actin or tubulin-based cytoskeletons and with Gpm6a gliding along membrane edges indicative for a func [...] | 0.515 |
Lrrn4 | Higd1b | ENSMUSP00000057005 | ENSMUSP00000021302 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | HIG1 domain family member 1B. | 0.446 |
Lrrn4 | Msln | ENSMUSP00000057005 | ENSMUSP00000158357 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Megakaryocyte-potentiating factor; Membrane-anchored forms may play a role in cellular adhesion. Belongs to the mesothelin family. | 0.538 |
Lrrn4 | Muc16 | ENSMUSP00000057005 | ENSMUSP00000147104 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Mucin 16. | 0.537 |
Lrrn4 | Nkain4 | ENSMUSP00000057005 | ENSMUSP00000099342 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Sodium/potassium-transporting ATPase subunit beta-1-interacting protein 4; Belongs to the NKAIN family. | 0.451 |
Lrrn4 | Upk1b | ENSMUSP00000057005 | ENSMUSP00000052469 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Uroplakin-1b; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in normal bladder epithelial physiology, possibly in regulating membrane permeability of superficial umbrella cells or in stabilizing the apical membrane through AUM/cytoskeletal interactions (By similarity). | 0.545 |
Lrrn4 | Upk3b | ENSMUSP00000057005 | ENSMUSP00000062312 | Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory. | Uroplakin-3b; Component of the asymmetric unit membrane (AUM); a highly specialized biomembrane elaborated by terminally differentiated urothelial cells. May play an important role in AUM-cytoskeleton interaction in terminally differentiated urothelial cells. It also contributes to the formation of urothelial glycocalyx which may play an important role in preventing bacterial adherence (By similarity). | 0.861 |
Msln | Gpm6a | ENSMUSP00000158357 | ENSMUSP00000033915 | Megakaryocyte-potentiating factor; Membrane-anchored forms may play a role in cellular adhesion. Belongs to the mesothelin family. | Neuronal membrane glycoprotein M6-a; Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. Gpm6a-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. Conflictingly, reports that induced cellular protrusions are simple membrane-wrapped tubules without actin or tubulin-based cytoskeletons and with Gpm6a gliding along membrane edges indicative for a func [...] | 0.448 |