STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Spink14Serine peptidase inhibitor, Kazal type 14. (96 aa)    
Predicted Functional Partners:
Zfp474
Zinc finger protein 474.
      
 0.706
Ccdc112
Coiled-coil domain-containing protein 112.
      
 0.607
Afap1l1
Actin filament-associated protein 1-like 1; May be involved in podosome and invadosome formation.
      
 0.606
Dtwd2
DTW domain-containing protein 2.
      
 0.604
Mon1b
Vacuolar fusion protein MON1 homolog B.
      
 0.538
Spink10
Serine protease inhibitor Kazal-type 10; Probable serine protease inhibitor.
      
 0.538
Spink13
Serine protease inhibitor Kazal-type 13; May be a serine protease inhibitor (By similarity). Essential for sperm maturation and fertility. Inhibits sperm acrosome reaction, protecting sperm from premature reaction (By similarity).
      
 0.538
Spink8
Serine protease inhibitor Kazal-type 8; Probable serine protease inhibitor.
      
 0.538
Glb1l3
Beta-galactosidase-1-like protein 3.
      
 0.538
Spink6
Serine protease inhibitor Kazal-type 6; Serine protease inhibitor selective for kallikreins. Efficiently inhibits KLK5 and human KLK2, KLK4, KLK5, KLK6, KLK7, KLK12, KLK13 and KLK14. Doesn't inhibit human KLK1 and KLK8.
   
  
 0.532
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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