node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bhlha9 | Lmbr1 | ENSMUSP00000050516 | ENSMUSP00000058405 | Class A basic helix-loop-helix protein 9; Transcription factor, which play a role in limb development. Is an essential player in the regulatory network governing transcription of genes implicated in limb morphogenesis. | Limb region 1 protein; Putative membrane receptor. | 0.654 |
Fam210b | Lmbr1 | ENSMUSP00000028995 | ENSMUSP00000058405 | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner. Belongs to the FAM210 family. | Limb region 1 protein; Putative membrane receptor. | 0.461 |
Letmd1 | Lmbr1 | ENSMUSP00000037546 | ENSMUSP00000058405 | LETM1 domain-containing protein 1; Involved in tumorigenesis and may function as a negative regulator of the p53/TP53. | Limb region 1 protein; Putative membrane receptor. | 0.545 |
Lmbr1 | Bhlha9 | ENSMUSP00000058405 | ENSMUSP00000050516 | Limb region 1 protein; Putative membrane receptor. | Class A basic helix-loop-helix protein 9; Transcription factor, which play a role in limb development. Is an essential player in the regulatory network governing transcription of genes implicated in limb morphogenesis. | 0.654 |
Lmbr1 | Fam210b | ENSMUSP00000058405 | ENSMUSP00000028995 | Limb region 1 protein; Putative membrane receptor. | Protein FAM210B, mitochondrial; Plays a role in erythroid differentiation. Involved in cell proliferation and tumor cell growth suppression. Involved in the metabolic reprogramming of cancer cells in a PDK4-dependent manner. Belongs to the FAM210 family. | 0.461 |
Lmbr1 | Letmd1 | ENSMUSP00000058405 | ENSMUSP00000037546 | Limb region 1 protein; Putative membrane receptor. | LETM1 domain-containing protein 1; Involved in tumorigenesis and may function as a negative regulator of the p53/TP53. | 0.545 |
Lmbr1 | Lmbrd1 | ENSMUSP00000058405 | ENSMUSP00000140783 | Limb region 1 protein; Putative membrane receptor. | Probable lysosomal cobalamin transporter; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity); Belongs to the LIMR family. LMBRD1 subfamily. | 0.614 |
Lmbr1 | Mctp1 | ENSMUSP00000058405 | ENSMUSP00000105212 | Limb region 1 protein; Putative membrane receptor. | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. | 0.574 |
Lmbr1 | Nom1 | ENSMUSP00000058405 | ENSMUSP00000001611 | Limb region 1 protein; Putative membrane receptor. | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus. | 0.592 |
Lmbr1 | Rnf32 | ENSMUSP00000058405 | ENSMUSP00000001247 | Limb region 1 protein; Putative membrane receptor. | RING finger protein 32; May play a role in sperm formation. | 0.773 |
Lmbr1 | Shh | ENSMUSP00000058405 | ENSMUSP00000002708 | Limb region 1 protein; Putative membrane receptor. | Sonic hedgehog protein N-product; [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity. Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN. Both activities occur in the reticulum endoplasmic. Once cleaved, ShhC is degraded in the endoplasmic reticulum. | 0.703 |
Lmbr1 | Wnt8b | ENSMUSP00000058405 | ENSMUSP00000042867 | Limb region 1 protein; Putative membrane receptor. | Protein Wnt-8b; Ligand for members of the frizzled family of seven transmembrane receptors. May play an important role in the development and differentiation of certain forebrain structures, notably the hippocampus; Belongs to the Wnt family. | 0.453 |
Lmbr1 | Zp2 | ENSMUSP00000058405 | ENSMUSP00000033207 | Limb region 1 protein; Putative membrane receptor. | Processed zona pellucida sperm-binding protein 2; Component of the zona pellucida, an extracellular matrix surrounding oocytes which mediates sperm binding, induction of the acrosome reaction and prevents post-fertilization polyspermy. The zona pellucida is composed of 3 to 4 glycoproteins, ZP1, ZP2, ZP3, and ZP4. ZP2 may act as a secondary sperm receptor. | 0.590 |
Lmbrd1 | Lmbr1 | ENSMUSP00000140783 | ENSMUSP00000058405 | Probable lysosomal cobalamin transporter; Probable lysosomal cobalamin transporter. Required to export cobalamin from lysosomes allowing its conversion to cofactors (By similarity); Belongs to the LIMR family. LMBRD1 subfamily. | Limb region 1 protein; Putative membrane receptor. | 0.614 |
Mctp1 | Lmbr1 | ENSMUSP00000105212 | ENSMUSP00000058405 | Multiple C2 and transmembrane domain-containing protein 1; Calcium sensor which is essential for the stabilization of normal baseline neurotransmitter release and for the induction and long-term maintenance of presynaptic homeostatic plasticity. | Limb region 1 protein; Putative membrane receptor. | 0.574 |
Nom1 | Lmbr1 | ENSMUSP00000001611 | ENSMUSP00000058405 | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus. | Limb region 1 protein; Putative membrane receptor. | 0.592 |
Nom1 | Rnf32 | ENSMUSP00000001611 | ENSMUSP00000001247 | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus. | RING finger protein 32; May play a role in sperm formation. | 0.768 |
Rnf32 | Lmbr1 | ENSMUSP00000001247 | ENSMUSP00000058405 | RING finger protein 32; May play a role in sperm formation. | Limb region 1 protein; Putative membrane receptor. | 0.773 |
Rnf32 | Nom1 | ENSMUSP00000001247 | ENSMUSP00000001611 | RING finger protein 32; May play a role in sperm formation. | Nucleolar MIF4G domain-containing protein 1; Plays a role in targeting PPP1CA to the nucleolus. | 0.768 |
Rnf32 | Shh | ENSMUSP00000001247 | ENSMUSP00000002708 | RING finger protein 32; May play a role in sperm formation. | Sonic hedgehog protein N-product; [Sonic hedgehog protein]: The C-terminal part of the sonic hedgehog protein precursor displays an autoproteolysis and a cholesterol transferase activity. Both activities result in the cleavage of the full-length protein into two parts (ShhN and ShhC) followed by the covalent attachment of a cholesterol moiety to the C-terminal of the newly generated ShhN. Both activities occur in the reticulum endoplasmic. Once cleaved, ShhC is degraded in the endoplasmic reticulum. | 0.424 |