STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Skint10Selection and upkeep of intraepithelial T-cells protein 10; May act by engaging a cell surface molecule on immature T- cells in the embryonic thymus; Belongs to the SKINT family. (354 aa)    
Predicted Functional Partners:
AU021092
UPF0764 protein C16orf89 homolog.
    
 
 0.649
Gm1110
Beta-galactosidase.
   
  
 0.647
Defb13
Beta-defensin 13; Has antibacterial activity.
   
  
 0.492
Vgll2
Transcription cofactor vestigial-like protein 2; May act as a specific coactivator for the mammalian TEFs. May play a role in the development of skeletal muscles.
      
 0.479
Sebox
Homeobox protein SEBOX; Probable transcription factor involved in the control of specification of mesoderm and endoderm; Belongs to the paired homeobox family.
      
 0.457
Lrrn4
Leucine-rich repeat neuronal protein 4; May play an important role in hippocampus-dependent long- lasting memory.
    
 
 0.440
Krt2
Keratin, type II cytoskeletal 2 epidermal; Probably contributes to terminal cornification (By similarity). Associated with keratinocyte activation, proliferation and keratinization (By similarity). Plays a role in the establishment of the epidermal barrier on plantar skin.
   
 
 0.418
Lrch4
Leucine-rich repeat and calponin homology domain-containing protein 4.
    
 
 0.417
Lypd6
Ly6/PLAUR domain-containing protein 6; Acts as a modulator of nicotinic acetylcholine receptors (nAChRs) function in the brain. Enhances nicotine-induced Ca(2+) influx through nAChRs. Acts as a positive regulator of Wnt/beta-catenin signaling (By similarity).
    
 
 0.405
Capn9
Calpain-9; Calcium-regulated non-lysosomal thiol-protease.
   
  
 0.400
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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