Export your current network:
... as a vector graphic:
SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc
... as short tabular text output:
TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)
... as tabular text output:
TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)
... as an XML summary:
structured XML interaction data, according to the 'PSI-MI' data standard
... protein node degrees:
node degree of proteins in your network (given the current score cut-off)
... network coordinates:
a flat-file format describing the coordinates and colors of nodes in the network
... protein sequences:
MFA: multi-fasta format - containing the aminoacid sequences in the network
... protein annotations:
a tab-delimited file describing the names, domains and descriptions of proteins in your network
... functional annotations:
a tab-delimited file containing all known functional terms of protiens in your network
Browse interactions in tabular form:
| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ddx28 | Esf1 | ENSMUSP00000058950 | ENSMUSP00000036523 | Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (By similarity); Belongs to the DEAD box helicase family. | ESF1 homolog; May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity). | 0.880 |
| Ddx28 | Gtpbp10 | ENSMUSP00000058950 | ENSMUSP00000111101 | Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (By similarity); Belongs to the DEAD box helicase family. | GTP-binding protein 10; May be involved in the ribosome maturation process. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.881 |
| Ddx28 | Malsu1 | ENSMUSP00000058950 | ENSMUSP00000122941 | Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (By similarity); Belongs to the DEAD box helicase family. | Mitochondrial assembly of ribosomal large subunit protein 1; Required for normal mitochondrial ribosome function and mitochondrial translation. May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S riboso [...] | 0.907 |
| Ddx28 | Mrm3 | ENSMUSP00000058950 | ENSMUSP00000042882 | Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (By similarity); Belongs to the DEAD box helicase family. | rRNA methyltransferase 3, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | 0.960 |
| Ddx28 | Mrpl4 | ENSMUSP00000058950 | ENSMUSP00000003386 | Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (By similarity); Belongs to the DEAD box helicase family. | 39S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL4 family. | 0.847 |
| Ddx28 | Mterf3 | ENSMUSP00000058950 | ENSMUSP00000021991 | Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (By similarity); Belongs to the DEAD box helicase family. | Transcription termination factor 3, mitochondrial; Binds promoter DNA and regulates initiation of transcription (By similarity). Required for normal mitochondrial transcription and translation, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function. Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit ; Belongs to the mTERF family. | 0.850 |
| Ddx28 | Mtg1 | ENSMUSP00000058950 | ENSMUSP00000036491 | Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (By similarity); Belongs to the DEAD box helicase family. | Mitochondrial ribosome-associated GTPase 1; Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity (By similarity). Displays mitochondrial GTPase activity (By similarity). | 0.850 |
| Ddx28 | Ngdn | ENSMUSP00000058950 | ENSMUSP00000022815 | Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (By similarity); Belongs to the DEAD box helicase family. | Neuroguidin; Inhibits mRNA translation in a cytoplasmic polyadenylation element (CPE)-dependent manner; Belongs to the SAS10 family. | 0.889 |
| Ddx28 | Rpusd4 | ENSMUSP00000058950 | ENSMUSP00000034543 | Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (By similarity); Belongs to the DEAD box helicase family. | Mitochondrial RNA pseudouridine synthase Rpusd4; Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome. Acts on position 39 in mitochondrial tRNA(Phe). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt- rRNA, controls 16S mt-rRNA abundance and is required for intra- mitochondrial translation. | 0.855 |
| Ddx28 | Utp3 | ENSMUSP00000058950 | ENSMUSP00000087896 | Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (By similarity); Belongs to the DEAD box helicase family. | Something about silencing protein 10; Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain. Belongs to the SAS10 family. | 0.889 |
| Esf1 | Ddx28 | ENSMUSP00000036523 | ENSMUSP00000058950 | ESF1 homolog; May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity). | Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (By similarity); Belongs to the DEAD box helicase family. | 0.880 |
| Esf1 | Ngdn | ENSMUSP00000036523 | ENSMUSP00000022815 | ESF1 homolog; May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity). | Neuroguidin; Inhibits mRNA translation in a cytoplasmic polyadenylation element (CPE)-dependent manner; Belongs to the SAS10 family. | 0.904 |
| Esf1 | Utp3 | ENSMUSP00000036523 | ENSMUSP00000087896 | ESF1 homolog; May constitute a novel regulatory system for basal transcription. Negatively regulates ABT1 (By similarity). | Something about silencing protein 10; Essential for gene silencing: has a role in the structure of silenced chromatin. Plays a role in the developing brain. Belongs to the SAS10 family. | 0.997 |
| Gtpbp10 | Ddx28 | ENSMUSP00000111101 | ENSMUSP00000058950 | GTP-binding protein 10; May be involved in the ribosome maturation process. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Probable ATP-dependent RNA helicase DDX28; Plays an essential role in facilitating the proper assembly of the mitochondrial large ribosomal subunit and its helicase activity is essential for this function. May be involved in RNA processing or transport. Has RNA and Mg(2+)-dependent ATPase activity (By similarity); Belongs to the DEAD box helicase family. | 0.881 |
| Gtpbp10 | Malsu1 | ENSMUSP00000111101 | ENSMUSP00000122941 | GTP-binding protein 10; May be involved in the ribosome maturation process. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Mitochondrial assembly of ribosomal large subunit protein 1; Required for normal mitochondrial ribosome function and mitochondrial translation. May play a role in ribosome biogenesis by preventing premature association of the 28S and 39S ribosomal subunits. Interacts with mitochondrial ribosomal protein L14 (MRPL14), probably blocking formation of intersubunit bridge B8, preventing association of the 28S and 39S ribosomal subunits. Addition to isolated mitochondrial ribosomal subunits partially inhibits translation, probably by interfering with the association of the 28S and 39S riboso [...] | 0.946 |
| Gtpbp10 | Mrm3 | ENSMUSP00000111101 | ENSMUSP00000042882 | GTP-binding protein 10; May be involved in the ribosome maturation process. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | rRNA methyltransferase 3, mitochondrial; S-adenosyl-L-methionine-dependent 2'-O-ribose methyltransferase that catalyzes the formation of 2'-O-methylguanosine at position 1370 (Gm1370) in the 16S mitochondrial large subunit ribosomal RNA (mtLSU rRNA), a conserved modification in the peptidyl transferase domain of the mtLSU rRNA. | 0.812 |
| Gtpbp10 | Mrpl4 | ENSMUSP00000111101 | ENSMUSP00000003386 | GTP-binding protein 10; May be involved in the ribosome maturation process. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 39S ribosomal protein L4, mitochondrial; Belongs to the universal ribosomal protein uL4 family. | 0.553 |
| Gtpbp10 | Mterf3 | ENSMUSP00000111101 | ENSMUSP00000021991 | GTP-binding protein 10; May be involved in the ribosome maturation process. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Transcription termination factor 3, mitochondrial; Binds promoter DNA and regulates initiation of transcription (By similarity). Required for normal mitochondrial transcription and translation, and for normal assembly of mitochondrial respiratory complexes. Required for normal mitochondrial function. Maintains 16S rRNA levels and functions in mitochondrial ribosome assembly by regulating the biogenesis of the 39S ribosomal subunit ; Belongs to the mTERF family. | 0.517 |
| Gtpbp10 | Mtg1 | ENSMUSP00000111101 | ENSMUSP00000036491 | GTP-binding protein 10; May be involved in the ribosome maturation process. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Mitochondrial ribosome-associated GTPase 1; Plays a role in the regulation of the mitochondrial ribosome assembly and of translational activity (By similarity). Displays mitochondrial GTPase activity (By similarity). | 0.861 |
| Gtpbp10 | Rpusd4 | ENSMUSP00000111101 | ENSMUSP00000034543 | GTP-binding protein 10; May be involved in the ribosome maturation process. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | Mitochondrial RNA pseudouridine synthase Rpusd4; Catalyzes uridine to pseudouridine isomerization (pseudouridylation) of different mitochondrial RNA substrates. Acts on position 1397 in 16S mitochondrial ribosomal RNA (16S mt-rRNA). This modification is required for the assembly of 16S mt-rRNA into a functional mitochondrial ribosome. Acts on position 39 in mitochondrial tRNA(Phe). As a component of a functional protein-RNA module, consisting of RCC1L, NGRN, RPUSD3, RPUSD4, TRUB2, FASTKD2 and 16S mt- rRNA, controls 16S mt-rRNA abundance and is required for intra- mitochondrial translation. | 0.760 |
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