4932438A13Rik protein (mouse) - STRING interaction network

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4932438A13Rik

Transmembrane protein KIAA1109. (5005 aa)

Predicted Functional Partners:

Adad1

0.866

Herc1

0.812

Zfp942

0.629

Mycbp2

0.589

Vps13b

0.549

Birc6

0.546

Gm5565

0.518

Als2cl

0.490

Nbas

0.489

Gm16223

0.489

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
4932438A13Rik	Adad1	ENSMUSP00000060199	ENSMUSP00000115260	Transmembrane protein KIAA1109.	Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA.	0.866
4932438A13Rik	Als2cl	ENSMUSP00000060199	ENSMUSP00000115718	Transmembrane protein KIAA1109.	ALS2 C-terminal-like protein; Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics (By similarity).	0.490
4932438A13Rik	Birc6	ENSMUSP00000060199	ENSMUSP00000136329	Transmembrane protein KIAA1109.	Baculoviral IAP repeat-containing protein 6; Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also [...]	0.546
4932438A13Rik	Gm16223	ENSMUSP00000060199	ENSMUSP00000084590	Transmembrane protein KIAA1109.	Predicted gene 16223.	0.489
4932438A13Rik	Gm5565	ENSMUSP00000060199	ENSMUSP00000143497	Transmembrane protein KIAA1109.	Predicted gene 5565.	0.518
4932438A13Rik	Herc1	ENSMUSP00000060199	ENSMUSP00000044801	Transmembrane protein KIAA1109.	HECT and RLD domain-containing E3 ubiquitin protein ligase family member 1.	0.812
4932438A13Rik	Mycbp2	ENSMUSP00000060199	ENSMUSP00000124710	Transmembrane protein KIAA1109.	E3 ubiquitin-protein ligase MYCBP2; Atypical E3 ubiquitin-protein ligase which specifically mediates ubiquitination of threonine and serine residues on target proteins, instead of ubiquitinating lysine residues (By similarity). Shows esterification activity towards both threonine and serine, with a preference for threonine, and acts via two essential catalytic cysteine residues that relay ubiquitin to its substrate via thioester intermediates (By similarity). Interacts with the E2 enzymes UBE2D1, UBE2D3, UBE2E1 and UBE2L3 (By similarity). Plays a key role in neural development, probabl [...]	0.589
4932438A13Rik	Nbas	ENSMUSP00000060199	ENSMUSP00000036082	Transmembrane protein KIAA1109.	Neuroblastoma-amplified sequence.	0.489
4932438A13Rik	Vps13b	ENSMUSP00000060199	ENSMUSP00000045490	Transmembrane protein KIAA1109.	Vacuolar protein sorting-associated protein 13B; May be involved in protein sorting in post Golgi membrane traffic; Belongs to the VPS13 family.	0.549
4932438A13Rik	Zfp942	ENSMUSP00000060199	ENSMUSP00000089494	Transmembrane protein KIAA1109.	Zinc finger protein 942.	0.629
Adad1	4932438A13Rik	ENSMUSP00000115260	ENSMUSP00000060199	Adenosine deaminase domain-containing protein 1; Plays a role in spermatogenesis. Binds to RNA but not to DNA.	Transmembrane protein KIAA1109.	0.866
Als2cl	4932438A13Rik	ENSMUSP00000115718	ENSMUSP00000060199	ALS2 C-terminal-like protein; Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics (By similarity).	Transmembrane protein KIAA1109.	0.490
Birc6	4932438A13Rik	ENSMUSP00000136329	ENSMUSP00000060199	Baculoviral IAP repeat-containing protein 6; Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also [...]	Transmembrane protein KIAA1109.	0.546
Birc6	Herc1	ENSMUSP00000136329	ENSMUSP00000044801	Baculoviral IAP repeat-containing protein 6; Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also [...]	HECT and RLD domain-containing E3 ubiquitin protein ligase family member 1.	0.669
Birc6	Mycbp2	ENSMUSP00000136329	ENSMUSP00000124710	Baculoviral IAP repeat-containing protein 6; Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also [...]	E3 ubiquitin-protein ligase MYCBP2; Atypical E3 ubiquitin-protein ligase which specifically mediates ubiquitination of threonine and serine residues on target proteins, instead of ubiquitinating lysine residues (By similarity). Shows esterification activity towards both threonine and serine, with a preference for threonine, and acts via two essential catalytic cysteine residues that relay ubiquitin to its substrate via thioester intermediates (By similarity). Interacts with the E2 enzymes UBE2D1, UBE2D3, UBE2E1 and UBE2L3 (By similarity). Plays a key role in neural development, probabl [...]	0.731
Birc6	Vps13b	ENSMUSP00000136329	ENSMUSP00000045490	Baculoviral IAP repeat-containing protein 6; Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also [...]	Vacuolar protein sorting-associated protein 13B; May be involved in protein sorting in post Golgi membrane traffic; Belongs to the VPS13 family.	0.552
Gm16223	4932438A13Rik	ENSMUSP00000084590	ENSMUSP00000060199	Predicted gene 16223.	Transmembrane protein KIAA1109.	0.489
Gm5565	4932438A13Rik	ENSMUSP00000143497	ENSMUSP00000060199	Predicted gene 5565.	Transmembrane protein KIAA1109.	0.518
Herc1	4932438A13Rik	ENSMUSP00000044801	ENSMUSP00000060199	HECT and RLD domain-containing E3 ubiquitin protein ligase family member 1.	Transmembrane protein KIAA1109.	0.812
Herc1	Birc6	ENSMUSP00000044801	ENSMUSP00000136329	HECT and RLD domain-containing E3 ubiquitin protein ligase family member 1.	Baculoviral IAP repeat-containing protein 6; Anti-apoptotic protein which can regulate cell death by controlling caspases and by acting as an E3 ubiquitin-protein ligase. Has an unusual ubiquitin conjugation system in that it could combine in a single polypeptide, ubiquitin conjugating (E2) with ubiquitin ligase (E3) activity, forming a chimeric E2/E3 ubiquitin ligase. Its tragets include CASP9 and DIABLO/SMAC. Acts as an inhibitor of CASP3, CASP7 and CASP9. Important regulator for the final stages of cytokinesis. Crucial for normal vesicle targeting to the site of abscission, but also [...]	0.669