STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Krtcap3Keratinocyte-associated protein 3; Belongs to the TMEM54 family. (240 aa)    
Predicted Functional Partners:
Ccdc121
Coiled-coil domain-containing 121.
      
 0.713
Ttc22
Tetratricopeptide repeat protein 22.
   
  
 0.710
Supt7l
STAGA complex 65 subunit gamma.
      
 0.657
Zfp512
Zinc finger protein 512; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family.
      
 0.642
Nrbp1
Nuclear receptor-binding protein; May play a role in subcellular trafficking between the endoplasmic reticulum and Golgi apparatus through interactions with the Rho-type GTPases.
 
    
 0.621
Slc4a1ap
Solute carrier family 4 (anion exchanger), member 1, adaptor protein.
      
 0.591
Fndc4
Fibronectin type III domain-containing protein 4; Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro- inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.
      
 0.579
Trmt10a
tRNA methyltransferase 10 homolog A; S-adenosyl-L-methionine-dependent guanine N(1)- methyltransferase that catalyzes the formation of N(1)-methylguanine at position 9 (m1G9) in tRNAs. Probably not able to catalyze formation of N(1)-methyladenine at position 9 (m1A9) in tRNAs. Belongs to the class IV-like SAM-binding methyltransferase superfamily. TRM10 family.
      
 0.556
Spatc1l
Speriolin-like protein; Belongs to the speriolin family.
      
 0.553
Zfp513
Zinc finger protein 513; Transcriptional regulator that plays a role in retinal development and maintenance.
   
  
 0.553
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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