STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Susd3Sushi domain-containing protein 3. (269 aa)    
Predicted Functional Partners:
Card19
Caspase recruitment domain-containing protein 19; Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B.
 
    0.531
Cped1
Cadherin-like and PC-esterase domain-containing 1.
      
 0.531
Krtcap3
Keratinocyte-associated protein 3; Belongs to the TMEM54 family.
   
  
 0.510
Sash3
SAM and SH3 domain-containing protein 3; May function as a signaling adapter protein in lymphocytes.
   
  
 0.489
Acy3
N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming); Plays an important role in deacetylating mercapturic acids in kidney proximal tubules. Also acts on N-acetyl-aromatic amino acids.
      
 0.470
Spint3
Serine peptidase inhibitor, Kunitz type, 3.
      
 0.459
Rasal3
RAS protein activator like-3; Functions as a Ras GTPase-activating protein. Plays an important role in the expansion and functions of natural killer T (NKT) cells in the liver by negatively regulating RAS activity and the down- stream ERK signaling pathway.
   
  
 0.458
Lrrc66
Leucine-rich repeat-containing protein 66.
   
  
 0.457
Naglu
Alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB).
   
  
 0.453
Esyt3
Extended synaptotagmin-3; Tethers the endoplasmic reticulum to the cell membrane and promotes the formation of appositions between the endoplasmic reticulum and the cell membrane. Binds glycerophospholipids in a barrel-like domain and may play a role in cellular lipid transport (By similarity). Belongs to the extended synaptotagmin family.
      
 0.444
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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