STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Defb10Beta-defensin 10; Has antibacterial activity. (73 aa)    
Predicted Functional Partners:
Defb35
Beta-defensin 35; Has antibacterial activity.
   
  
 0.802
Defb13
Beta-defensin 13; Has antibacterial activity.
   
  
 0.727
Defb15
Beta-defensin 15; Has antibacterial activity.
   
  
 0.704
Defb7
Beta-defensin 7; Has bactericidal activity; Belongs to the beta-defensin family. LAP/TAP subfamily.
   
  
 0.691
Defb33
Beta-defensin 33; Has antibacterial activity; Belongs to the beta-defensin family.
      
 0.611
Defb40
Beta-defensin 40; Has antibacterial activity.
   
  
 0.603
Defb18
Beta-defensin 18; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.574
Defb20
Beta-defensin 20; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.560
Defb5
Beta-defensin 5; Has antibacterial activity; Belongs to the beta-defensin family.
   
  
 0.513
Defb37
Beta-defensin 37; Has antibacterial activity.
   
  
 0.478
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.