STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
BpifcBPI fold-containing family C protein. (507 aa)    
Predicted Functional Partners:
Tmem239
Transmembrane protein 239.
   
  
 0.692
Spag7
Sperm-associated antigen 7.
      
 0.609
Bpifa5
BPI fold-containing family A member 5; May play a role in innate immunity in the oral cavity. Belongs to the BPI/LBP/Plunc superfamily. Plunc family.
   
  
 0.577
Bpifa1
BPI fold-containing family A member 1; Lipid-binding protein which shows high specificity for the surfactant phospholipid dipalmitoylphosphatidylcholine (DPPC) (By similarity). Plays a role in the innate immune responses of the upper airways. Reduces the surface tension in secretions from airway epithelia and inhibits the formation of biofilm by pathogenic Gram-negative bacteria, such as P.aeruginosa and K.pneumoniae. Negatively regulates proteolytic cleavage of SCNN1G, an event that is required for activation of the epithelial sodium channel (ENaC), and thereby contributes to airway s [...]
   
  
 0.549
Iqcd
Dynein regulatory complex protein 10; Component of the nexin-dynein regulatory complex (N-DRC), a key regulator of ciliary/flagellar motility which maintains the alignment and integrity of the distal axoneme and regulates microtubule sliding in motile axonemes; Belongs to the DRC10 family.
      
 0.548
Platr25
Pluripotency-associated transcript 25.
      
 0.512
Fam160b2
Protein FAM160B2.
   
  
 0.482
Gm14409
Predicted gene 14409.
      
 0.479
Plekha4
Pleckstrin homology domain-containing family A member 4; Binds specifically to phosphatidylinositol 3-phosphate (PtdIns3P), but not to other phosphoinositides.
   
  
 0.464
Sdr16c6
Short-chain dehydrogenase/reductase family 16C member 6; Belongs to the short-chain dehydrogenases/reductases (SDR) family.
   
  
 0.461
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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