node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bnip3l | Spata18 | ENSMUSP00000022634 | ENSMUSP00000064308 | BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; Induces apoptosis. Interacts with viral and cellular anti- apoptosis proteins. Can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. Inhibits apoptosis induced by BNIP3. Involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates in mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. The physical interaction of SPATA18/MIE [...] | Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...] | 0.651 |
Ccdc146 | Cfap161 | ENSMUSP00000110900 | ENSMUSP00000011298 | Coiled-coil domain-containing 146. | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | 0.684 |
Ccdc146 | Lrrc23 | ENSMUSP00000110900 | ENSMUSP00000032218 | Coiled-coil domain-containing 146. | Leucine-rich repeat-containing protein 23. | 0.651 |
Ccdc146 | Rsph14 | ENSMUSP00000110900 | ENSMUSP00000131632 | Coiled-coil domain-containing 146. | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | 0.675 |
Ccdc146 | Saxo2 | ENSMUSP00000110900 | ENSMUSP00000057993 | Coiled-coil domain-containing 146. | Stabilizer of axonemal microtubules 2; Belongs to the FAM154 family. | 0.662 |
Ccdc146 | Spata18 | ENSMUSP00000110900 | ENSMUSP00000064308 | Coiled-coil domain-containing 146. | Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...] | 0.626 |
Cfap161 | Ccdc146 | ENSMUSP00000011298 | ENSMUSP00000110900 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Coiled-coil domain-containing 146. | 0.684 |
Cfap161 | Lrrc23 | ENSMUSP00000011298 | ENSMUSP00000032218 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Leucine-rich repeat-containing protein 23. | 0.725 |
Cfap161 | Rsph14 | ENSMUSP00000011298 | ENSMUSP00000131632 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | 0.744 |
Cfap161 | Saxo2 | ENSMUSP00000011298 | ENSMUSP00000057993 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Stabilizer of axonemal microtubules 2; Belongs to the FAM154 family. | 0.734 |
Cfap161 | Spata18 | ENSMUSP00000011298 | ENSMUSP00000064308 | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...] | 0.635 |
Lrrc23 | Ccdc146 | ENSMUSP00000032218 | ENSMUSP00000110900 | Leucine-rich repeat-containing protein 23. | Coiled-coil domain-containing 146. | 0.651 |
Lrrc23 | Cfap161 | ENSMUSP00000032218 | ENSMUSP00000011298 | Leucine-rich repeat-containing protein 23. | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | 0.725 |
Lrrc23 | Rsph14 | ENSMUSP00000032218 | ENSMUSP00000131632 | Leucine-rich repeat-containing protein 23. | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | 0.658 |
Lrrc23 | Saxo2 | ENSMUSP00000032218 | ENSMUSP00000057993 | Leucine-rich repeat-containing protein 23. | Stabilizer of axonemal microtubules 2; Belongs to the FAM154 family. | 0.654 |
Lrrc23 | Spata18 | ENSMUSP00000032218 | ENSMUSP00000064308 | Leucine-rich repeat-containing protein 23. | Mitochondria-eating protein; Key regulator of mitochondrial quality that mediates the repairing or degradation of unhealthy mitochondria in response to mitochondrial damage. Mediator of mitochondrial protein catabolic process (also named MALM) by mediating the degradation of damaged proteins inside mitochondria by promoting the accumulation in the mitochondrial matrix of hydrolases that are characteristic of the lysosomal lumen. Also involved in mitochondrion degradation of damaged mitochondria by promoting the formation of vacuole-like structures (named MIV), which engulf and degrade [...] | 0.602 |
Rsph14 | Ccdc146 | ENSMUSP00000131632 | ENSMUSP00000110900 | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | Coiled-coil domain-containing 146. | 0.675 |
Rsph14 | Cfap161 | ENSMUSP00000131632 | ENSMUSP00000011298 | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | Cilia- and flagella-associated protein 161; May play a role in motile cilia function, possibly by acting on dynein arm assembly. | 0.744 |
Rsph14 | Lrrc23 | ENSMUSP00000131632 | ENSMUSP00000032218 | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | Leucine-rich repeat-containing protein 23. | 0.658 |
Rsph14 | Saxo2 | ENSMUSP00000131632 | ENSMUSP00000057993 | Radial spoke head 14 homolog; Belongs to the flagellar radial spoke RSP14 family. | Stabilizer of axonemal microtubules 2; Belongs to the FAM154 family. | 0.715 |