STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Defb34Beta-defensin 34; Has antibacterial activity. (81 aa)    
Predicted Functional Partners:
Defb46
Beta-defensin 50.
   
  
 0.721
Prr36
Proline-rich 36.
      
 0.711
Defb12
Beta-defensin 12; Has antibacterial activity.
   
  
 0.577
Olfr478
Olfactory receptor 478; Potential odorant receptor; Belongs to the G-protein coupled receptor 1 family.
   
    0.511
Tcaf3
TRPM8 channel-associated factor 3; May play a role in the regulation of the cation channel TRPM8 activity.
      
 0.491
Defb13
Beta-defensin 13; Has antibacterial activity.
   
  
 0.456
Defb35
Beta-defensin 35; Has antibacterial activity.
   
  
 0.420
Olfr608
Olfactory receptor.
   
    0.418
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.