node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Abhd10 | Abhd11 | ENSMUSP00000065282 | ENSMUSP00000043041 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial. | Protein ABHD11; Belongs to the AB hydrolase superfamily. | 0.557 |
Abhd10 | Abhd12b | ENSMUSP00000065282 | ENSMUSP00000134568 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial. | Abhydrolase domain-containing 12B. | 0.551 |
Abhd10 | Abhd13 | ENSMUSP00000065282 | ENSMUSP00000116130 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial. | Protein ABHD13. | 0.577 |
Abhd10 | Abhd16a | ENSMUSP00000065282 | ENSMUSP00000007251 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial. | Phosphatidylserine lipase ABHD16A; Phosphatidylserine (PS) lipase that mediates the hydrolysis of phosphatidylserine to generate lysophosphatidylserine (LPS). LPS constitutes a class of signaling lipids that regulates immunological and neurological processes. Has no activity towards diacylglycerol, triacylglycerol or lysophosphatidylserine lipase (By similarity). Also has monoacylglycerol lipase activity, with preference for 1-(9Z,12Z- octadecadienoyl)-glycerol (1-LG) and 2-glyceryl-15-deoxy-Delta(12,14)- prostaglandin J2 (15d-PGJ(2)-G). Belongs to the AB hydrolase superfamily. ABHD16 [...] | 0.568 |
Abhd10 | Abhd17a | ENSMUSP00000065282 | ENSMUSP00000003436 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial. | Alpha/beta hydrolase domain-containing protein 17A; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards NRAS. Has depalmitoylating activity towards DLG4/PSD95. May have depalmitoylating activity towars MAP6. | 0.712 |
Abhd10 | Abhd17b | ENSMUSP00000065282 | ENSMUSP00000056099 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial. | Alpha/beta hydrolase domain-containing protein 17B; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards DLG4/PSD95. Has depalmitoylating activity towards GAP43. Has depalmitoylating activity towards MAP6. Has depalmitoylating activity towards NRAS (By similarity). | 0.597 |
Abhd10 | Abhd3 | ENSMUSP00000065282 | ENSMUSP00000113137 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial. | Phospholipase ABHD3; Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids. | 0.624 |
Abhd10 | Abhd6 | ENSMUSP00000065282 | ENSMUSP00000129169 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial. | Monoacylglycerol lipase ABHD6; Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids. Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formati [...] | 0.577 |
Abhd10 | Dip2b | ENSMUSP00000065282 | ENSMUSP00000097777 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial. | Disco-interacting protein 2 homolog B. | 0.628 |
Abhd10 | Lypla1 | ENSMUSP00000065282 | ENSMUSP00000027036 | Mycophenolic acid acyl-glucuronide esterase, mitochondrial. | Acyl-protein thioesterase 1; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity (By similarity); Belongs to the AB hydrolase superfamily. AB hydrolase 2 family. | 0.570 |
Abhd11 | Abhd10 | ENSMUSP00000043041 | ENSMUSP00000065282 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Mycophenolic acid acyl-glucuronide esterase, mitochondrial. | 0.557 |
Abhd11 | Abhd13 | ENSMUSP00000043041 | ENSMUSP00000116130 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Protein ABHD13. | 0.494 |
Abhd11 | Abhd16a | ENSMUSP00000043041 | ENSMUSP00000007251 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Phosphatidylserine lipase ABHD16A; Phosphatidylserine (PS) lipase that mediates the hydrolysis of phosphatidylserine to generate lysophosphatidylserine (LPS). LPS constitutes a class of signaling lipids that regulates immunological and neurological processes. Has no activity towards diacylglycerol, triacylglycerol or lysophosphatidylserine lipase (By similarity). Also has monoacylglycerol lipase activity, with preference for 1-(9Z,12Z- octadecadienoyl)-glycerol (1-LG) and 2-glyceryl-15-deoxy-Delta(12,14)- prostaglandin J2 (15d-PGJ(2)-G). Belongs to the AB hydrolase superfamily. ABHD16 [...] | 0.550 |
Abhd11 | Abhd17b | ENSMUSP00000043041 | ENSMUSP00000056099 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Alpha/beta hydrolase domain-containing protein 17B; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards DLG4/PSD95. Has depalmitoylating activity towards GAP43. Has depalmitoylating activity towards MAP6. Has depalmitoylating activity towards NRAS (By similarity). | 0.451 |
Abhd11 | Abhd3 | ENSMUSP00000043041 | ENSMUSP00000113137 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Phospholipase ABHD3; Phospholipase that may play a role in phospholipids remodeling. May selectively cleave myristate (C14)-containing phosphatidylcholines through its predominant phospholipase 1 activity, cleaving preferentially acyl groups in sn1 position. In parallel, may have a minor phospholipase 2 activity acting on acyl groups in position sn2. In addition to (C14)-containing phosphatidylcholines, may also act on other medium-chain-containing and oxidatively truncated phospholipids. | 0.606 |
Abhd11 | Abhd6 | ENSMUSP00000043041 | ENSMUSP00000129169 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Monoacylglycerol lipase ABHD6; Lipase that preferentially hydrolysis medium-chain saturated monoacylglycerols including 2-arachidonoylglycerol. Through 2-arachidonoylglycerol degradation may regulate endocannabinoid signaling pathways. Also has a lysophosphatidyl lipase activity with a preference for lysophosphatidylglycerol among other lysophospholipids. Also able to degrade bis(monoacylglycero)phosphate (BMP) and constitutes the major enzyme for BMP catabolism. BMP, also known as lysobisphosphatidic acid, is enriched in late endosomes and lysosomes and plays a key role in the formati [...] | 0.713 |
Abhd11 | Lypla1 | ENSMUSP00000043041 | ENSMUSP00000027036 | Protein ABHD11; Belongs to the AB hydrolase superfamily. | Acyl-protein thioesterase 1; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Has depalmitoylating activity toward KCNMA1. Has low lysophospholipase activity (By similarity); Belongs to the AB hydrolase superfamily. AB hydrolase 2 family. | 0.588 |
Abhd12b | Abhd10 | ENSMUSP00000134568 | ENSMUSP00000065282 | Abhydrolase domain-containing 12B. | Mycophenolic acid acyl-glucuronide esterase, mitochondrial. | 0.551 |
Abhd12b | Abhd13 | ENSMUSP00000134568 | ENSMUSP00000116130 | Abhydrolase domain-containing 12B. | Protein ABHD13. | 0.432 |
Abhd12b | Abhd16a | ENSMUSP00000134568 | ENSMUSP00000007251 | Abhydrolase domain-containing 12B. | Phosphatidylserine lipase ABHD16A; Phosphatidylserine (PS) lipase that mediates the hydrolysis of phosphatidylserine to generate lysophosphatidylserine (LPS). LPS constitutes a class of signaling lipids that regulates immunological and neurological processes. Has no activity towards diacylglycerol, triacylglycerol or lysophosphatidylserine lipase (By similarity). Also has monoacylglycerol lipase activity, with preference for 1-(9Z,12Z- octadecadienoyl)-glycerol (1-LG) and 2-glyceryl-15-deoxy-Delta(12,14)- prostaglandin J2 (15d-PGJ(2)-G). Belongs to the AB hydrolase superfamily. ABHD16 [...] | 0.601 |