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Cyp3a25 protein (mouse) - STRING interaction network
"Cyp3a25" - Cytochrome P450 3A25 in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cyp3a25Cytochrome P450 3A25; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (503 aa)    
Predicted Functional Partners:
Cyp2c50
Cytochrome P450 2C50; Metabolizes arachidonic acid to several midchain and omega-terminal hydroxyeicosatetraenoic acids (HETE) (490 aa)
   
0.975
Cyp2c37
Cytochrome P450 2C37; Metabolizes arachidonic acid to produce 12- hydroxyeicosatetraenoic acid (HETE); Belongs to the cytochrome P450 family (490 aa)
   
0.975
Ugt2b1
UDP-glucuronosyltransferase; UDP glucuronosyltransferase 2 family, polypeptide B1; Belongs to the UDP-glycosyltransferase family (529 aa)
     
  0.975
Cyp3a11
Cytochrome P450 3A11; Catalyzes erythromycin N-demethylation, nifedipine oxidation and testosterone 6 beta-hydroxylation; Belongs to the cytochrome P450 family (504 aa)
   
 
0.975
Cyp2d26
Cytochrome P450 2D26; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (500 aa)
   
0.975
Cyp2c54
Cytochrome P450 2C54; Metabolizes arachidonic acid mainly to 12- hydroxyeicosatetraenoic acid (HETE); Belongs to the cytochrome P450 family (490 aa)
   
0.973
Cyp2d10
Cytochrome P450 2D10; Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics (504 aa)
   
0.972
Cyp2a12
Cytochrome P450 2A12; Highly active in the 7-alpha-hydroxylation of testosterone (492 aa)
   
0.971
Ugt2b5
UDP-glucuronosyltransferase 2B17; UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds (530 aa)
     
  0.970
Cyp2c29
Cytochrome P450 2C29; Metabolizes arachidonic acid to produce 14,15-cis- epoxyeicosatrienoic acid (EET) (490 aa)
   
0.962
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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