node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
B2m | Cd74 | ENSMUSP00000099534 | ENSMUSP00000095171 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | 0.826 |
B2m | Cd8a | ENSMUSP00000099534 | ENSMUSP00000068123 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | T-cell surface glycoprotein CD8 alpha chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Sr [...] | 0.984 |
B2m | H2-Aa | ENSMUSP00000099534 | ENSMUSP00000046105 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | H-2 class II histocompatibility antigen, A-B alpha chain. | 0.616 |
B2m | H2-DMa | ENSMUSP00000099534 | ENSMUSP00000037088 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | Class II histocompatibility antigen, M alpha chain; Plays a critical role in catalyzing the release of class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides. | 0.591 |
B2m | H2-Eb1 | ENSMUSP00000099534 | ENSMUSP00000158533 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | H-2 class II histocompatibility antigen, E-B beta chain; Belongs to the MHC class II family. | 0.652 |
B2m | H2-Oa | ENSMUSP00000099534 | ENSMUSP00000025192 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | Histocompatibility 2, O region alpha locus; Belongs to the MHC class II family. | 0.617 |
B2m | H2-Ob | ENSMUSP00000099534 | ENSMUSP00000092985 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | Histocompatibility 2, O region beta locus. | 0.619 |
B2m | H2-Q10 | ENSMUSP00000099534 | ENSMUSP00000134163 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | H-2 class I histocompatibility antigen, Q10 alpha chain; Involved in the presentation of foreign antigens to the immune system. | 0.986 |
B2m | Klra3 | ENSMUSP00000099534 | ENSMUSP00000107629 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | Killer cell lectin-like receptor 3; Receptor on natural killer (NK) cells for class I MHC. | 0.945 |
B2m | Tapbp | ENSMUSP00000099534 | ENSMUSP00000025161 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | Tapasin; Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading). | 0.999 |
Cd74 | B2m | ENSMUSP00000095171 | ENSMUSP00000099534 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | 0.826 |
Cd74 | H2-Aa | ENSMUSP00000095171 | ENSMUSP00000046105 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | H-2 class II histocompatibility antigen, A-B alpha chain. | 0.999 |
Cd74 | H2-DMa | ENSMUSP00000095171 | ENSMUSP00000037088 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | Class II histocompatibility antigen, M alpha chain; Plays a critical role in catalyzing the release of class II HLA-associated invariant chain-derived peptides (CLIP) from newly synthesized class II HLA molecules and freeing the peptide binding site for acquisition of antigenic peptides. | 0.990 |
Cd74 | H2-Eb1 | ENSMUSP00000095171 | ENSMUSP00000158533 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | H-2 class II histocompatibility antigen, E-B beta chain; Belongs to the MHC class II family. | 0.999 |
Cd74 | H2-Oa | ENSMUSP00000095171 | ENSMUSP00000025192 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | Histocompatibility 2, O region alpha locus; Belongs to the MHC class II family. | 0.991 |
Cd74 | H2-Ob | ENSMUSP00000095171 | ENSMUSP00000092985 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | Histocompatibility 2, O region beta locus. | 0.975 |
Cd74 | H2-Q10 | ENSMUSP00000095171 | ENSMUSP00000134163 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | H-2 class I histocompatibility antigen, Q10 alpha chain; Involved in the presentation of foreign antigens to the immune system. | 0.823 |
Cd74 | Tapbp | ENSMUSP00000095171 | ENSMUSP00000025161 | H-2 class II histocompatibility antigen gamma chain; Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to compartments where peptide loading of class II takes place. Enhance also the stimulation of T-cell responses through interaction with CD44. | Tapasin; Involved in the association of MHC class I with transporter associated with antigen processing (TAP) and in the assembly of MHC class I with peptide (peptide loading). | 0.643 |
Cd8a | B2m | ENSMUSP00000068123 | ENSMUSP00000099534 | T-cell surface glycoprotein CD8 alpha chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Sr [...] | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | 0.984 |
Cd8a | H2-Q10 | ENSMUSP00000068123 | ENSMUSP00000134163 | T-cell surface glycoprotein CD8 alpha chain; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class I molecule:peptide complex. The antigens presented by class I peptides are derived from cytosolic proteins while class II derived from extracellular proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class I proteins presented by antigen presenting cells (APCs). In turn, recruits the Sr [...] | H-2 class I histocompatibility antigen, Q10 alpha chain; Involved in the presentation of foreign antigens to the immune system. | 0.780 |