node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
2610002M06Rik | Chmp1b | ENSMUSP00000113588 | ENSMUSP00000147285 | Charged multivesicular body protein 1b-2; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require t [...] | Charged multivesicular body protein 1b-1; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require t [...] | 0.902 |
2610002M06Rik | Dcbld1 | ENSMUSP00000113588 | ENSMUSP00000068203 | Charged multivesicular body protein 1b-2; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require t [...] | Discoidin, CUB and LCCL domain-containing protein 1. | 0.538 |
2610002M06Rik | Fam229b | ENSMUSP00000113588 | ENSMUSP00000063508 | Charged multivesicular body protein 1b-2; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require t [...] | Protein FAM229B; Belongs to the FAM229 family. | 0.538 |
2610002M06Rik | Magee2 | ENSMUSP00000113588 | ENSMUSP00000033575 | Charged multivesicular body protein 1b-2; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require t [...] | Melanoma antigen, family E, 2. | 0.537 |
Chmp1b | 2610002M06Rik | ENSMUSP00000147285 | ENSMUSP00000113588 | Charged multivesicular body protein 1b-1; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require t [...] | Charged multivesicular body protein 1b-2; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require t [...] | 0.902 |
Chmp1b | Dcbld1 | ENSMUSP00000147285 | ENSMUSP00000068203 | Charged multivesicular body protein 1b-1; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require t [...] | Discoidin, CUB and LCCL domain-containing protein 1. | 0.538 |
Chmp1b | Fam229b | ENSMUSP00000147285 | ENSMUSP00000063508 | Charged multivesicular body protein 1b-1; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require t [...] | Protein FAM229B; Belongs to the FAM229 family. | 0.538 |
Chmp1b | Magee2 | ENSMUSP00000147285 | ENSMUSP00000033575 | Charged multivesicular body protein 1b-1; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require t [...] | Melanoma antigen, family E, 2. | 0.537 |
Crkl | Dcbld1 | ENSMUSP00000006293 | ENSMUSP00000068203 | Crk-like protein; May mediate the transduction of intracellular signals. | Discoidin, CUB and LCCL domain-containing protein 1. | 0.584 |
Dcbld1 | 2610002M06Rik | ENSMUSP00000068203 | ENSMUSP00000113588 | Discoidin, CUB and LCCL domain-containing protein 1. | Charged multivesicular body protein 1b-2; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require t [...] | 0.538 |
Dcbld1 | Chmp1b | ENSMUSP00000068203 | ENSMUSP00000147285 | Discoidin, CUB and LCCL domain-containing protein 1. | Charged multivesicular body protein 1b-1; Probable peripherally associated component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require t [...] | 0.538 |
Dcbld1 | Crkl | ENSMUSP00000068203 | ENSMUSP00000006293 | Discoidin, CUB and LCCL domain-containing protein 1. | Crk-like protein; May mediate the transduction of intracellular signals. | 0.584 |
Dcbld1 | Dcun1d3 | ENSMUSP00000068203 | ENSMUSP00000058968 | Discoidin, CUB and LCCL domain-containing protein 1. | DCN1-like protein 3; Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane. | 0.523 |
Dcbld1 | Fam229b | ENSMUSP00000068203 | ENSMUSP00000063508 | Discoidin, CUB and LCCL domain-containing protein 1. | Protein FAM229B; Belongs to the FAM229 family. | 0.658 |
Dcbld1 | Magee2 | ENSMUSP00000068203 | ENSMUSP00000033575 | Discoidin, CUB and LCCL domain-containing protein 1. | Melanoma antigen, family E, 2. | 0.481 |
Dcbld1 | Mrps17 | ENSMUSP00000068203 | ENSMUSP00000112779 | Discoidin, CUB and LCCL domain-containing protein 1. | 28S ribosomal protein S17, mitochondrial; Belongs to the universal ribosomal protein uS17 family. | 0.489 |
Dcbld1 | P3h3 | ENSMUSP00000068203 | ENSMUSP00000023958 | Discoidin, CUB and LCCL domain-containing protein 1. | Prolyl 3-hydroxylase 3; Part of a complex composed of PLOD1, P3H3 and P3H4 that catalyzes hydroxylation of lysine residues in collagen alpha chains and is required for normal assembly and cross-linkling of collagen fibrils. Required for normal hydroxylation of lysine residues in type I collagen chains in skin, bone, tendon, aorta and cornea. Required for normal skin stability via its role in hydroxylation of lysine residues in collagen alpha chains and in collagen fibril assembly. Apparently not required for normal prolyl 3-hydroxylation on collagen chains, possibly because it function [...] | 0.559 |
Dcbld1 | Secisbp2l | ENSMUSP00000068203 | ENSMUSP00000055772 | Discoidin, CUB and LCCL domain-containing protein 1. | Selenocysteine insertion sequence-binding protein 2-like; Binds SECIS (Sec insertion sequence) elements present on selenocysteine (Sec) protein mRNAs, but does not promote Sec incorporation into selenoproteins. | 0.516 |
Dcbld1 | Zcchc14 | ENSMUSP00000068203 | ENSMUSP00000040360 | Discoidin, CUB and LCCL domain-containing protein 1. | Zinc finger CCHC domain-containing protein 14. | 0.583 |
Dcun1d3 | Dcbld1 | ENSMUSP00000058968 | ENSMUSP00000068203 | DCN1-like protein 3; Antagonizes DCUN1D1-mediated CUL1 neddylation by sequestering CUL1 at the cell membrane. | Discoidin, CUB and LCCL domain-containing protein 1. | 0.523 |