node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Asb17 | Eaf1 | ENSMUSP00000041293 | ENSMUSP00000022446 | Ankyrin repeat and SOCS box protein 17; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | 0.648 |
Asb17 | Mill1 | ENSMUSP00000041293 | ENSMUSP00000069083 | Ankyrin repeat and SOCS box protein 17; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | MHC I-like leukocyte 1; Belongs to the MHC class I family. | 0.654 |
Asb17 | Olfr449 | ENSMUSP00000041293 | ENSMUSP00000145322 | Ankyrin repeat and SOCS box protein 17; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Olfactory receptor. | 0.529 |
Asb17 | Vmn2r106 | ENSMUSP00000041293 | ENSMUSP00000126534 | Ankyrin repeat and SOCS box protein 17; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | Vomeronasal 2, receptor 106. | 0.520 |
B2m | Epo | ENSMUSP00000099534 | ENSMUSP00000106667 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. | 0.441 |
B2m | Mill1 | ENSMUSP00000099534 | ENSMUSP00000069083 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | MHC I-like leukocyte 1; Belongs to the MHC class I family. | 0.418 |
B2m | Tfr2 | ENSMUSP00000099534 | ENSMUSP00000142720 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | Transferrin receptor protein 2; Mediates cellular uptake of transferrin-bound iron in a non- iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation; Belongs to the peptidase M28 family. M28B subfamily. | 0.864 |
B2m | Tfrc | ENSMUSP00000099534 | ENSMUSP00000023486 | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Upon stimulation, positively regulates T and B cell proliferation through iron uptake ; Belongs to t [...] | 0.951 |
Eaf1 | Asb17 | ENSMUSP00000022446 | ENSMUSP00000041293 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | Ankyrin repeat and SOCS box protein 17; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.648 |
Eaf1 | Mill1 | ENSMUSP00000022446 | ENSMUSP00000069083 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | MHC I-like leukocyte 1; Belongs to the MHC class I family. | 0.473 |
Eaf1 | Olfr449 | ENSMUSP00000022446 | ENSMUSP00000145322 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | Olfactory receptor. | 0.480 |
Eaf1 | Vmn2r106 | ENSMUSP00000022446 | ENSMUSP00000126534 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | Vomeronasal 2, receptor 106. | 0.457 |
Epo | B2m | ENSMUSP00000106667 | ENSMUSP00000099534 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | 0.441 |
Epo | Mill1 | ENSMUSP00000106667 | ENSMUSP00000069083 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. | MHC I-like leukocyte 1; Belongs to the MHC class I family. | 0.402 |
Epo | Tfr2 | ENSMUSP00000106667 | ENSMUSP00000142720 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. | Transferrin receptor protein 2; Mediates cellular uptake of transferrin-bound iron in a non- iron dependent manner. May be involved in iron metabolism, hepatocyte function and erythrocyte differentiation; Belongs to the peptidase M28 family. M28B subfamily. | 0.577 |
Epo | Tfrc | ENSMUSP00000106667 | ENSMUSP00000023486 | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. | Transferrin receptor protein 1; Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). Upon stimulation, positively regulates T and B cell proliferation through iron uptake ; Belongs to t [...] | 0.694 |
Mill1 | Asb17 | ENSMUSP00000069083 | ENSMUSP00000041293 | MHC I-like leukocyte 1; Belongs to the MHC class I family. | Ankyrin repeat and SOCS box protein 17; May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. | 0.654 |
Mill1 | B2m | ENSMUSP00000069083 | ENSMUSP00000099534 | MHC I-like leukocyte 1; Belongs to the MHC class I family. | Beta-2-microglobulin; Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system; Belongs to the beta-2-microglobulin family. | 0.418 |
Mill1 | Eaf1 | ENSMUSP00000069083 | ENSMUSP00000022446 | MHC I-like leukocyte 1; Belongs to the MHC class I family. | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | 0.473 |
Mill1 | Epo | ENSMUSP00000069083 | ENSMUSP00000106667 | MHC I-like leukocyte 1; Belongs to the MHC class I family. | Erythropoietin; Hormone involved in the regulation of erythrocyte proliferation and differentiation and the maintenance of a physiological level of circulating erythrocyte mass. Binds to EPOR leading to EPOR dimerization and JAK2 activation thereby activating specific downstream effectors, including STAT1 and STAT3. | 0.402 |