node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cdk2ap1 | Chd3 | ENSMUSP00000031341 | ENSMUSP00000104301 | Cyclin-dependent kinase 2-associated protein 1; specific inhibitor of the cell-cycle kinase CDK2. | Chromodomain helicase DNA-binding protein 3. | 0.879 |
Cdk2ap1 | Chd4 | ENSMUSP00000031341 | ENSMUSP00000060054 | Cyclin-dependent kinase 2-associated protein 1; specific inhibitor of the cell-cycle kinase CDK2. | Chromodomain-helicase-DNA-binding protein 4; Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. | 0.679 |
Cdk2ap1 | Gatad2a | ENSMUSP00000031341 | ENSMUSP00000070229 | Cyclin-dependent kinase 2-associated protein 1; specific inhibitor of the cell-cycle kinase CDK2. | Transcriptional repressor p66 alpha; Transcriptional repressor (By similarity). Enhances MBD2- mediated repression. Efficient repression requires the presence of GATAD2B (By similarity). | 0.966 |
Cdk2ap1 | Gatad2b | ENSMUSP00000031341 | ENSMUSP00000142514 | Cyclin-dependent kinase 2-associated protein 1; specific inhibitor of the cell-cycle kinase CDK2. | Transcriptional repressor p66-beta; Transcriptional repressor (By similarity). Enhances MBD2- mediated repression. Efficient repression requires the presence of GATAD2A (By similarity). Targets MBD3 to discrete loci in the nucleus (By similarity). Plays a role in synapse development (By similarity). | 0.895 |
Cdk2ap1 | Hdac1 | ENSMUSP00000031341 | ENSMUSP00000099657 | Cyclin-dependent kinase 2-associated protein 1; specific inhibitor of the cell-cycle kinase CDK2. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.751 |
Cdk2ap1 | Hdac2 | ENSMUSP00000031341 | ENSMUSP00000019911 | Cyclin-dependent kinase 2-associated protein 1; specific inhibitor of the cell-cycle kinase CDK2. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor co [...] | 0.637 |
Cdk2ap1 | Mta2 | ENSMUSP00000031341 | ENSMUSP00000093959 | Cyclin-dependent kinase 2-associated protein 1; specific inhibitor of the cell-cycle kinase CDK2. | Metastasis-associated protein MTA2; May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins. | 0.517 |
Cdk2ap1 | Mta3 | ENSMUSP00000031341 | ENSMUSP00000068931 | Cyclin-dependent kinase 2-associated protein 1; specific inhibitor of the cell-cycle kinase CDK2. | Metastasis-associated protein MTA3; Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6 (By similarity). | 0.510 |
Cdk2ap1 | Rbbp4 | ENSMUSP00000031341 | ENSMUSP00000099658 | Cyclin-dependent kinase 2-associated protein 1; specific inhibitor of the cell-cycle kinase CDK2. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome re [...] | 0.851 |
Cdk2ap1 | Rbbp7 | ENSMUSP00000031341 | ENSMUSP00000033720 | Cyclin-dependent kinase 2-associated protein 1; specific inhibitor of the cell-cycle kinase CDK2. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and [...] | 0.707 |
Chd3 | Cdk2ap1 | ENSMUSP00000104301 | ENSMUSP00000031341 | Chromodomain helicase DNA-binding protein 3. | Cyclin-dependent kinase 2-associated protein 1; specific inhibitor of the cell-cycle kinase CDK2. | 0.879 |
Chd3 | Chd4 | ENSMUSP00000104301 | ENSMUSP00000060054 | Chromodomain helicase DNA-binding protein 3. | Chromodomain-helicase-DNA-binding protein 4; Component of the histone deacetylase NuRD complex which participates in the remodeling of chromatin by deacetylating histones. | 0.999 |
Chd3 | Gatad2a | ENSMUSP00000104301 | ENSMUSP00000070229 | Chromodomain helicase DNA-binding protein 3. | Transcriptional repressor p66 alpha; Transcriptional repressor (By similarity). Enhances MBD2- mediated repression. Efficient repression requires the presence of GATAD2B (By similarity). | 0.998 |
Chd3 | Gatad2b | ENSMUSP00000104301 | ENSMUSP00000142514 | Chromodomain helicase DNA-binding protein 3. | Transcriptional repressor p66-beta; Transcriptional repressor (By similarity). Enhances MBD2- mediated repression. Efficient repression requires the presence of GATAD2A (By similarity). Targets MBD3 to discrete loci in the nucleus (By similarity). Plays a role in synapse development (By similarity). | 0.985 |
Chd3 | Hdac1 | ENSMUSP00000104301 | ENSMUSP00000099657 | Chromodomain helicase DNA-binding protein 3. | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Deacetylates SP proteins, SP1 and SP3, and regulates their function. Component of the BRG1-RB1-HDAC1 complex, which negatively regulates the CREST-mediated transcription in resting neurons. Upon calcium st [...] | 0.999 |
Chd3 | Hdac2 | ENSMUSP00000104301 | ENSMUSP00000019911 | Chromodomain helicase DNA-binding protein 3. | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes (By similarity). Forms transcriptional repressor complexes by associating with MAD, SIN3, YY1 and N-COR. Interacts in the late S-phase of DNA-replication with DNMT1 in the other transcriptional repressor co [...] | 0.999 |
Chd3 | Mta2 | ENSMUSP00000104301 | ENSMUSP00000093959 | Chromodomain helicase DNA-binding protein 3. | Metastasis-associated protein MTA2; May be involved in the regulation of gene expression as repressor and activator. The repression might be related to covalent modification of histone proteins. | 0.985 |
Chd3 | Mta3 | ENSMUSP00000104301 | ENSMUSP00000068931 | Chromodomain helicase DNA-binding protein 3. | Metastasis-associated protein MTA3; Plays a role in maintenance of the normal epithelial architecture through the repression of SNAI1 transcription in a histone deacetylase-dependent manner, and thus the regulation of E-cadherin levels. Contributes to transcriptional repression by BCL6 (By similarity). | 0.932 |
Chd3 | Rbbp4 | ENSMUSP00000104301 | ENSMUSP00000099658 | Chromodomain helicase DNA-binding protein 3. | Histone-binding protein RBBP4; Core histone-binding subunit that may target chromatin assembly factors, chromatin remodeling factors and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the chromatin assembly factor 1 (CAF-1) complex, which is required for chromatin assembly following DNA replication and DNA repair; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome re [...] | 0.999 |
Chd3 | Rbbp7 | ENSMUSP00000104301 | ENSMUSP00000033720 | Chromodomain helicase DNA-binding protein 3. | Histone-binding protein RBBP7; Core histone-binding subunit that may target chromatin remodeling factors, histone acetyltransferases and histone deacetylases to their histone substrates in a manner that is regulated by nucleosomal DNA. Component of several complexes which regulate chromatin metabolism. These include the type B histone acetyltransferase (HAT) complex, which is required for chromatin assembly following DNA replication; the core histone deacetylase (HDAC) complex, which promotes histone deacetylation and consequent transcriptional repression; the nucleosome remodeling and [...] | 0.999 |