node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Cdkn3 | Cgrrf1 | ENSMUSP00000070575 | ENSMUSP00000070548 | Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner (By similarity). | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | 0.495 |
Cgref1 | Cgrrf1 | ENSMUSP00000031051 | ENSMUSP00000070548 | Cell growth regulator with EF hand domain protein 1; Mediates cell-cell adhesion in a calcium-dependent manner. Able to inhibit growth in several cell lines (By similarity). | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | 0.517 |
Cgrrf1 | Cdkn3 | ENSMUSP00000070548 | ENSMUSP00000070575 | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | Cyclin-dependent kinase inhibitor 3; May play a role in cell cycle regulation. Dual specificity phosphatase active toward substrates containing either phosphotyrosine or phosphoserine residues. Dephosphorylates CDK2 at 'Thr-160' in a cyclin-dependent manner (By similarity). | 0.495 |
Cgrrf1 | Cgref1 | ENSMUSP00000070548 | ENSMUSP00000031051 | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | Cell growth regulator with EF hand domain protein 1; Mediates cell-cell adhesion in a calcium-dependent manner. Able to inhibit growth in several cell lines (By similarity). | 0.517 |
Cgrrf1 | Cnih1 | ENSMUSP00000070548 | ENSMUSP00000015903 | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | Protein cornichon homolog 1; Involved in the selective transport and maturation of TGF- alpha family proteins. | 0.574 |
Cgrrf1 | Fam8a1 | ENSMUSP00000070548 | ENSMUSP00000097144 | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | Family with sequence similarity 8, member A1. | 0.544 |
Cgrrf1 | Gmfb | ENSMUSP00000070548 | ENSMUSP00000107448 | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | Glia maturation factor beta; This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells; Belongs to the actin-binding proteins ADF family. GMF subfamily. | 0.555 |
Cgrrf1 | Rnf170 | ENSMUSP00000070548 | ENSMUSP00000014022 | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | E3 ubiquitin-protein ligase RNF170; E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells. | 0.572 |
Cgrrf1 | Rnft1 | ENSMUSP00000070548 | ENSMUSP00000020827 | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | E3 ubiquitin-protein ligase RNFT1; E3 ubiquitin-protein ligase that acts in the endoplasmic reticulum (ER)-associated degradation (ERAD) pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER) for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis. | 0.655 |
Cgrrf1 | Sel1l | ENSMUSP00000070548 | ENSMUSP00000021347 | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | Protein sel-1 homolog 1; Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Enhances SYVN1 stability. Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells. May play a role in Notch signaling. | 0.524 |
Cgrrf1 | Ube2j1 | ENSMUSP00000070548 | ENSMUSP00000118333 | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | Ubiquitin-conjugating enzyme E2 J1; Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD); Belongs to the ubiquitin-conjugating enzyme family. | 0.493 |
Cgrrf1 | Ube2j2 | ENSMUSP00000070548 | ENSMUSP00000024056 | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | Ubiquitin-conjugating enzyme E2 J2; Catalyzes the covalent attachment of ubiquitin to other proteins. Seems to function in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD). Belongs to the ubiquitin-conjugating enzyme family. | 0.566 |
Cnih1 | Cgrrf1 | ENSMUSP00000015903 | ENSMUSP00000070548 | Protein cornichon homolog 1; Involved in the selective transport and maturation of TGF- alpha family proteins. | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | 0.574 |
Cnih1 | Gmfb | ENSMUSP00000015903 | ENSMUSP00000107448 | Protein cornichon homolog 1; Involved in the selective transport and maturation of TGF- alpha family proteins. | Glia maturation factor beta; This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells; Belongs to the actin-binding proteins ADF family. GMF subfamily. | 0.529 |
Fam8a1 | Cgrrf1 | ENSMUSP00000097144 | ENSMUSP00000070548 | Family with sequence similarity 8, member A1. | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | 0.544 |
Fam8a1 | Rnf170 | ENSMUSP00000097144 | ENSMUSP00000014022 | Family with sequence similarity 8, member A1. | E3 ubiquitin-protein ligase RNF170; E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved in ITPR1 turnover in resting cells. | 0.578 |
Fam8a1 | Sel1l | ENSMUSP00000097144 | ENSMUSP00000021347 | Family with sequence similarity 8, member A1. | Protein sel-1 homolog 1; Plays a role in the endoplasmic reticulum quality control (ERQC) system also called ER-associated degradation (ERAD) involved in ubiquitin-dependent degradation of misfolded endoplasmic reticulum proteins. Enhances SYVN1 stability. Plays a role in LPL maturation and secretion. Required for normal differentiation of the pancreas epithelium, and for normal exocrine function and survival of pancreatic cells. May play a role in Notch signaling. | 0.952 |
Fam8a1 | Ube2j1 | ENSMUSP00000097144 | ENSMUSP00000118333 | Family with sequence similarity 8, member A1. | Ubiquitin-conjugating enzyme E2 J1; Catalyzes the covalent attachment of ubiquitin to other proteins. Functions in the selective degradation of misfolded membrane proteins from the endoplasmic reticulum (ERAD); Belongs to the ubiquitin-conjugating enzyme family. | 0.646 |
Gmfb | Cgrrf1 | ENSMUSP00000107448 | ENSMUSP00000070548 | Glia maturation factor beta; This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells; Belongs to the actin-binding proteins ADF family. GMF subfamily. | Cell growth regulator with RING finger domain protein 1; Able to inhibit growth in several cell lines. | 0.555 |
Gmfb | Cnih1 | ENSMUSP00000107448 | ENSMUSP00000015903 | Glia maturation factor beta; This protein causes differentiation of brain cells, stimulation of neural regeneration, and inhibition of proliferation of tumor cells; Belongs to the actin-binding proteins ADF family. GMF subfamily. | Protein cornichon homolog 1; Involved in the selective transport and maturation of TGF- alpha family proteins. | 0.529 |