node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bdh1 | Pcyt1a | ENSMUSP00000110882 | ENSMUSP00000078721 | D-beta-hydroxybutyrate dehydrogenase, mitochondrial. | Choline-phosphate cytidylyltransferase A; Controls phosphatidylcholine synthesis; Belongs to the cytidylyltransferase family. | 0.571 |
Bdh1 | Slc51a | ENSMUSP00000110882 | ENSMUSP00000046286 | D-beta-hydroxybutyrate dehydrogenase, mitochondrial. | Organic solute transporter subunit alpha; Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. | 0.404 |
Bdh1 | Ubxn7 | ENSMUSP00000110882 | ENSMUSP00000110804 | D-beta-hydroxybutyrate dehydrogenase, mitochondrial. | UBX domain-containing protein 7; Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates (By similarity). | 0.583 |
Bdh1 | Wdr53 | ENSMUSP00000110882 | ENSMUSP00000023474 | D-beta-hydroxybutyrate dehydrogenase, mitochondrial. | WD repeat-containing protein 53; Belongs to the WD repeat WDR53 family. | 0.603 |
Bdh1 | Zdhhc19 | ENSMUSP00000110882 | ENSMUSP00000070727 | D-beta-hydroxybutyrate dehydrogenase, mitochondrial. | Palmitoyltransferase ZDHHC19; Palmitoyltransferase that mediates palmitoylation of STAT3 and RRAS. Palmitoylation of STAT3 induces the homodimerization and transcriptional activation of STAT3, thereby, promoting inflammation and cancer. Palmitoylation of RRAS is linked to cell viability. May be involved in S-stearoylation of STAT3. | 0.567 |
Cep19 | Pcyt1a | ENSMUSP00000110822 | ENSMUSP00000078721 | Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes. | Choline-phosphate cytidylyltransferase A; Controls phosphatidylcholine synthesis; Belongs to the cytidylyltransferase family. | 0.476 |
Cep19 | Smco1 | ENSMUSP00000110822 | ENSMUSP00000090873 | Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes. | Single-pass membrane and coiled-coil domain-containing protein 1. | 0.656 |
Cep19 | Tm4sf19 | ENSMUSP00000110822 | ENSMUSP00000110802 | Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes. | Transmembrane 4 L six family member 19. | 0.494 |
Cep19 | Ubxn7 | ENSMUSP00000110822 | ENSMUSP00000110804 | Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes. | UBX domain-containing protein 7; Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates (By similarity). | 0.612 |
Cep19 | Wdr53 | ENSMUSP00000110822 | ENSMUSP00000023474 | Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes. | WD repeat-containing protein 53; Belongs to the WD repeat WDR53 family. | 0.571 |
Cep19 | Zdhhc19 | ENSMUSP00000110822 | ENSMUSP00000070727 | Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes. | Palmitoyltransferase ZDHHC19; Palmitoyltransferase that mediates palmitoylation of STAT3 and RRAS. Palmitoylation of STAT3 induces the homodimerization and transcriptional activation of STAT3, thereby, promoting inflammation and cancer. Palmitoylation of RRAS is linked to cell viability. May be involved in S-stearoylation of STAT3. | 0.470 |
Golga7 | Zdhhc19 | ENSMUSP00000112935 | ENSMUSP00000070727 | Golgin subfamily A member 7; May be involved in protein transport from Golgi to cell surface. The ZDHHC9-GOLGA7 complex is a palmitoyltransferase specific for HRAS and NRAS (By similarity). | Palmitoyltransferase ZDHHC19; Palmitoyltransferase that mediates palmitoylation of STAT3 and RRAS. Palmitoylation of STAT3 induces the homodimerization and transcriptional activation of STAT3, thereby, promoting inflammation and cancer. Palmitoylation of RRAS is linked to cell viability. May be involved in S-stearoylation of STAT3. | 0.473 |
Pcyt1a | Bdh1 | ENSMUSP00000078721 | ENSMUSP00000110882 | Choline-phosphate cytidylyltransferase A; Controls phosphatidylcholine synthesis; Belongs to the cytidylyltransferase family. | D-beta-hydroxybutyrate dehydrogenase, mitochondrial. | 0.571 |
Pcyt1a | Cep19 | ENSMUSP00000078721 | ENSMUSP00000110822 | Choline-phosphate cytidylyltransferase A; Controls phosphatidylcholine synthesis; Belongs to the cytidylyltransferase family. | Centrosomal protein of 19 kDa; Required for ciliation. Recruits the RABL2B GTPase to the ciliary base to initiate ciliation. After specifically capturing the activated GTP-bound RABL2B, the CEP19-RABL2B complex binds intraflagellar transport (IFT) complex B from the large pool pre-docked at the base of the cilium and thus triggers its entry into the cilia. Involved in the early steps in cilia formation by recruiting the ciliary vesicles (CVs) to the distal end of the mother centriole where they fuse to initiate cilium assembly. Involved in microtubule (MT) anchoring at centrosomes. | 0.476 |
Pcyt1a | Slc51a | ENSMUSP00000078721 | ENSMUSP00000046286 | Choline-phosphate cytidylyltransferase A; Controls phosphatidylcholine synthesis; Belongs to the cytidylyltransferase family. | Organic solute transporter subunit alpha; Essential component of the Ost-alpha/Ost-beta complex, a heterodimer that acts as the intestinal basolateral transporter responsible for bile acid export from enterocytes into portal blood. Efficiently transports the major species of bile acids. | 0.417 |
Pcyt1a | Smco1 | ENSMUSP00000078721 | ENSMUSP00000090873 | Choline-phosphate cytidylyltransferase A; Controls phosphatidylcholine synthesis; Belongs to the cytidylyltransferase family. | Single-pass membrane and coiled-coil domain-containing protein 1. | 0.478 |
Pcyt1a | Tm4sf19 | ENSMUSP00000078721 | ENSMUSP00000110802 | Choline-phosphate cytidylyltransferase A; Controls phosphatidylcholine synthesis; Belongs to the cytidylyltransferase family. | Transmembrane 4 L six family member 19. | 0.418 |
Pcyt1a | Ubxn7 | ENSMUSP00000078721 | ENSMUSP00000110804 | Choline-phosphate cytidylyltransferase A; Controls phosphatidylcholine synthesis; Belongs to the cytidylyltransferase family. | UBX domain-containing protein 7; Ubiquitin-binding adapter that links a subset of NEDD8- associated cullin ring ligases (CRLs) to the segregase VCP/p97, to regulate turnover of their ubiquitination substrates (By similarity). | 0.524 |
Pcyt1a | Wdr53 | ENSMUSP00000078721 | ENSMUSP00000023474 | Choline-phosphate cytidylyltransferase A; Controls phosphatidylcholine synthesis; Belongs to the cytidylyltransferase family. | WD repeat-containing protein 53; Belongs to the WD repeat WDR53 family. | 0.522 |
Pcyt1a | Zdhhc19 | ENSMUSP00000078721 | ENSMUSP00000070727 | Choline-phosphate cytidylyltransferase A; Controls phosphatidylcholine synthesis; Belongs to the cytidylyltransferase family. | Palmitoyltransferase ZDHHC19; Palmitoyltransferase that mediates palmitoylation of STAT3 and RRAS. Palmitoylation of STAT3 induces the homodimerization and transcriptional activation of STAT3, thereby, promoting inflammation and cancer. Palmitoylation of RRAS is linked to cell viability. May be involved in S-stearoylation of STAT3. | 0.531 |