node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Enthd1 | Katna1 | ENSMUSP00000155166 | ENSMUSP00000132514 | ENTH domain-containing 1. | Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. The function in regulating microtubule dynamics at spindle poles seems to depend on the association of [...] | 0.525 |
Enthd1 | Prdm10 | ENSMUSP00000155166 | ENSMUSP00000074104 | ENTH domain-containing 1. | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | 0.495 |
Enthd1 | Slitrk1 | ENSMUSP00000155166 | ENSMUSP00000097897 | ENTH domain-containing 1. | SLIT and NTRK-like protein 1; It is involved in synaptogenesis and promotes excitatory synapse differentiation (By similarity). Enhances neuronal dendrite outgrowth ; Belongs to the SLITRK family. | 0.486 |
Glce | Prdm10 | ENSMUSP00000139949 | ENSMUSP00000074104 | D-glucuronyl C5-epimerase; Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins. Belongs to the D-glucuronyl C5-epimerase family. | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | 0.458 |
Katna1 | Enthd1 | ENSMUSP00000132514 | ENSMUSP00000155166 | Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. The function in regulating microtubule dynamics at spindle poles seems to depend on the association of [...] | ENTH domain-containing 1. | 0.525 |
Katna1 | Prdm10 | ENSMUSP00000132514 | ENSMUSP00000074104 | Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. The function in regulating microtubule dynamics at spindle poles seems to depend on the association of [...] | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | 0.490 |
Katna1 | Slitrk1 | ENSMUSP00000132514 | ENSMUSP00000097897 | Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. The function in regulating microtubule dynamics at spindle poles seems to depend on the association of [...] | SLIT and NTRK-like protein 1; It is involved in synaptogenesis and promotes excitatory synapse differentiation (By similarity). Enhances neuronal dendrite outgrowth ; Belongs to the SLITRK family. | 0.600 |
Nrg4 | Prdm10 | ENSMUSP00000130929 | ENSMUSP00000074104 | Pro-neuregulin-4, membrane-bound isoform; Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors. Belongs to the neuregulin family. | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | 0.508 |
Osgepl1 | Prdm10 | ENSMUSP00000110128 | ENSMUSP00000074104 | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. Belongs to the KAE1 / TsaD family. | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | 0.455 |
Prdm10 | Enthd1 | ENSMUSP00000074104 | ENSMUSP00000155166 | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | ENTH domain-containing 1. | 0.495 |
Prdm10 | Glce | ENSMUSP00000074104 | ENSMUSP00000139949 | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | D-glucuronyl C5-epimerase; Converts D-glucuronic acid residues adjacent to N-sulfate sugar residues to L-iduronic acid residues, both in maturing heparan sulfate (HS) and heparin chains. This is important for further modifications that determine the specificity of interactions between these glycosaminoglycans and proteins. Belongs to the D-glucuronyl C5-epimerase family. | 0.458 |
Prdm10 | Katna1 | ENSMUSP00000074104 | ENSMUSP00000132514 | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. The function in regulating microtubule dynamics at spindle poles seems to depend on the association of [...] | 0.490 |
Prdm10 | Nrg4 | ENSMUSP00000074104 | ENSMUSP00000130929 | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | Pro-neuregulin-4, membrane-bound isoform; Low affinity ligand for the ERBB4 tyrosine kinase receptor. Concomitantly recruits ERBB1 and ERBB2 coreceptors, resulting in ligand-stimulated tyrosine phosphorylation and activation of the ERBB receptors. Does not bind to the ERBB1, ERBB2 and ERBB3 receptors. Belongs to the neuregulin family. | 0.508 |
Prdm10 | Osgepl1 | ENSMUSP00000074104 | ENSMUSP00000110128 | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | Probable tRNA N6-adenosine threonylcarbamoyltransferase, mitochondrial; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in mitochondrial tRNAs that read codons beginning with adenine. Probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. Involved in mitochondrial genome maintenance. Belongs to the KAE1 / TsaD family. | 0.455 |
Prdm10 | Prdm8 | ENSMUSP00000074104 | ENSMUSP00000108583 | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | PR domain zinc finger protein 8; Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3. Histone methyltransferase activity has not been confirmed in other species. Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR. Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation. In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival. | 0.523 |
Prdm10 | Setd4 | ENSMUSP00000074104 | ENSMUSP00000156723 | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | SET domain-containing protein 4; Belongs to the class V-like SAM-binding methyltransferase superfamily. SETD4 family. | 0.497 |
Prdm10 | Setmar | ENSMUSP00000074104 | ENSMUSP00000048225 | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | Histone-lysine N-methyltransferase SETMAR; Histone methyltransferase that methylates 'Lys-4' and 'Lys- 36' of histone H3, 2 specific tags for epigenetic transcriptional activation. Specifically mediates dimethylation of H3 'Lys-36'. Belongs to the class V-like SAM-binding methyltransferase superfamily. | 0.462 |
Prdm10 | Slitrk1 | ENSMUSP00000074104 | ENSMUSP00000097897 | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | SLIT and NTRK-like protein 1; It is involved in synaptogenesis and promotes excitatory synapse differentiation (By similarity). Enhances neuronal dendrite outgrowth ; Belongs to the SLITRK family. | 0.526 |
Prdm10 | Smyd4 | ENSMUSP00000074104 | ENSMUSP00000047505 | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | SET and MYND domain-containing protein 4. | 0.457 |
Prdm8 | Prdm10 | ENSMUSP00000108583 | ENSMUSP00000074104 | PR domain zinc finger protein 8; Probable histone methyltransferase, preferentially acting on 'Lys-9' of histone H3. Histone methyltransferase activity has not been confirmed in other species. Involved in the control of steroidogenesis through transcriptional repression of steroidogenesis marker genes such as CYP17A1 and LHCGR. Forms with BHLHE22 a transcriptional repressor complex controlling genes involved in neural development and neuronal differentiation. In the retina, it is required for rod bipolar and type 2 OFF-cone bipolar cell survival. | PR domain zinc finger protein 10; May be involved in transcriptional regulation. | 0.523 |