node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
4933409K07Rik | A930033H14Rik | ENSMUSP00000136168 | ENSMUSP00000126322 | annotation not available | RIKEN cDNA A930033H14 gene. | 0.707 |
4933409K07Rik | Pyroxd2 | ENSMUSP00000136168 | ENSMUSP00000075825 | annotation not available | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.552 |
A930033H14Rik | 4933409K07Rik | ENSMUSP00000126322 | ENSMUSP00000136168 | RIKEN cDNA A930033H14 gene. | annotation not available | 0.707 |
A930033H14Rik | LOC108169010 | ENSMUSP00000126322 | ENSMUSP00000137502 | RIKEN cDNA A930033H14 gene. | Protein FAM205A-2-like. | 0.707 |
A930033H14Rik | Pyroxd2 | ENSMUSP00000126322 | ENSMUSP00000075825 | RIKEN cDNA A930033H14 gene. | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.495 |
Coq2 | Coq3 | ENSMUSP00000031262 | ENSMUSP00000029909 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 0.934 |
Coq2 | Fdft1 | ENSMUSP00000031262 | ENSMUSP00000153671 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway; Belongs to the phytoene/squalene synthase family. | 0.519 |
Coq2 | Gm35339 | ENSMUSP00000031262 | ENSMUSP00000146420 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Predicted gene, 35339. | 0.484 |
Coq2 | Ndufaf6 | ENSMUSP00000031262 | ENSMUSP00000062039 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6; Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages. May play a role in the biogenesis of MT-ND1 (By similarity); Belongs to the NDUFAF6 family. | 0.506 |
Coq2 | Pyroxd2 | ENSMUSP00000031262 | ENSMUSP00000075825 | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.576 |
Coq3 | Coq2 | ENSMUSP00000029909 | ENSMUSP00000031262 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.934 |
Coq3 | Ndufaf6 | ENSMUSP00000029909 | ENSMUSP00000062039 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | NADH dehydrogenase (ubiquinone) complex I, assembly factor 6; Involved in the assembly of mitochondrial NADH:ubiquinone oxidoreductase complex (complex I) at early stages. May play a role in the biogenesis of MT-ND1 (By similarity); Belongs to the NDUFAF6 family. | 0.405 |
Coq3 | Pyroxd2 | ENSMUSP00000029909 | ENSMUSP00000075825 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.523 |
Fdft1 | Coq2 | ENSMUSP00000153671 | ENSMUSP00000031262 | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway; Belongs to the phytoene/squalene synthase family. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.519 |
Fdft1 | Pyroxd2 | ENSMUSP00000153671 | ENSMUSP00000075825 | Squalene synthase; Critical branch point enzyme of isoprenoid biosynthesis that is thought to regulate the flux of isoprene intermediates through the sterol pathway; Belongs to the phytoene/squalene synthase family. | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.781 |
Gm35339 | Coq2 | ENSMUSP00000146420 | ENSMUSP00000031262 | Predicted gene, 35339. | 4-hydroxybenzoate polyprenyltransferase, mitochondrial; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of coenzyme Q (CoQ) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate. | 0.484 |
Gm35339 | Pyroxd2 | ENSMUSP00000146420 | ENSMUSP00000075825 | Predicted gene, 35339. | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.705 |
LOC108169010 | A930033H14Rik | ENSMUSP00000137502 | ENSMUSP00000126322 | Protein FAM205A-2-like. | RIKEN cDNA A930033H14 gene. | 0.707 |
LOC108169010 | Pyroxd2 | ENSMUSP00000137502 | ENSMUSP00000075825 | Protein FAM205A-2-like. | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.552 |
Nat8 | Pyroxd2 | ENSMUSP00000032073 | ENSMUSP00000075825 | N-acetyltransferase 8; Acetylates the free alpha-amino group of cysteine S- conjugates to form mercapturic acids. This is the final step in a major route for detoxification of a wide variety of reactive electrophiles which starts with their incorporation into glutathione S-conjugates. The glutathione S-conjugates are then further processed into cysteine S-conjugates and finally mercapturic acids which are water soluble and can be readily excreted in urine or bile. Alternatively, may have a lysine N-acetyltransferase activity catalyzing peptidyl-lysine N6- acetylation of various protein [...] | Pyridine nucleotide-disulfide oxidoreductase domain-containing protein 2; Probable oxidoreductase. | 0.522 |