node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
4833439L19Rik | Zfp280c | ENSMUSP00000026989 | ENSMUSP00000075933 | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth (By similarity). | Zinc finger protein 280C; May function as a transcription factor. | 0.552 |
Adnp2 | Cbx1 | ENSMUSP00000068560 | ENSMUSP00000091475 | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Chromobox protein homolog 1; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | 0.631 |
Adnp2 | Cbx3 | ENSMUSP00000068560 | ENSMUSP00000031862 | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Chromobox protein homolog 3; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Probably involved in the repression of many genes located in euchromatin, such as E2F1, MYC and CDC25A. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin- like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box [...] | 0.600 |
Adnp2 | Mphosph8 | ENSMUSP00000068560 | ENSMUSP00000112170 | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | M-phase phosphoprotein 8; Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression. Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3, as well as MORC2. Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; [...] | 0.491 |
Adnp2 | Zfp280c | ENSMUSP00000068560 | ENSMUSP00000075933 | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | Zinc finger protein 280C; May function as a transcription factor. | 0.523 |
Cbx1 | Adnp2 | ENSMUSP00000091475 | ENSMUSP00000068560 | Chromobox protein homolog 1; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.631 |
Cbx1 | Cbx3 | ENSMUSP00000091475 | ENSMUSP00000031862 | Chromobox protein homolog 1; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | Chromobox protein homolog 3; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Probably involved in the repression of many genes located in euchromatin, such as E2F1, MYC and CDC25A. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin- like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box [...] | 0.782 |
Cbx1 | Zfp280c | ENSMUSP00000091475 | ENSMUSP00000075933 | Chromobox protein homolog 1; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | Zinc finger protein 280C; May function as a transcription factor. | 0.491 |
Cbx3 | Adnp2 | ENSMUSP00000031862 | ENSMUSP00000068560 | Chromobox protein homolog 3; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Probably involved in the repression of many genes located in euchromatin, such as E2F1, MYC and CDC25A. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin- like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box [...] | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.600 |
Cbx3 | Cbx1 | ENSMUSP00000031862 | ENSMUSP00000091475 | Chromobox protein homolog 3; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Probably involved in the repression of many genes located in euchromatin, such as E2F1, MYC and CDC25A. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin- like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box [...] | Chromobox protein homolog 1; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor (LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane. | 0.782 |
Cbx3 | Zfp280c | ENSMUSP00000031862 | ENSMUSP00000075933 | Chromobox protein homolog 3; Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Probably involved in the repression of many genes located in euchromatin, such as E2F1, MYC and CDC25A. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. Contributes to the conversion of local chromatin to a heterochromatin- like repressive state through H3 'Lys-9' trimethylation, mediates the recruitment of the methyltransferases SUV39H1 and/or SUV39H2 by the PER complex to the E-box [...] | Zinc finger protein 280C; May function as a transcription factor. | 0.500 |
Crybg2 | Zfp280c | ENSMUSP00000114099 | ENSMUSP00000075933 | Crystallin beta-gamma domain-containing 2; Belongs to the beta/gamma-crystallin family. | Zinc finger protein 280C; May function as a transcription factor. | 0.505 |
Cwc27 | Zfp280c | ENSMUSP00000022228 | ENSMUSP00000075933 | Spliceosome-associated protein CWC27 homolog; As part of the spliceosome, plays a role in pre-mRNA splicing. Probable inactive PPIase with no peptidyl-prolyl cis-trans isomerase activity; Belongs to the cyclophilin-type PPIase family. | Zinc finger protein 280C; May function as a transcription factor. | 0.493 |
Mphosph8 | Adnp2 | ENSMUSP00000112170 | ENSMUSP00000068560 | M-phase phosphoprotein 8; Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression. Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3, as well as MORC2. Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; [...] | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.491 |
Mphosph8 | Zfp280c | ENSMUSP00000112170 | ENSMUSP00000075933 | M-phase phosphoprotein 8; Heterochromatin component that specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes recruitment of proteins that mediate epigenetic repression. Mediates recruitment of the HUSH complex to H3K9me3 sites: the HUSH complex is recruited to genomic loci rich in H3K9me3 and is required to maintain transcriptional silencing by promoting recruitment of SETDB1, a histone methyltransferase that mediates further deposition of H3K9me3, as well as MORC2. Binds H3K9me and promotes DNA methylation by recruiting DNMT3A to target CpG sites; [...] | Zinc finger protein 280C; May function as a transcription factor. | 0.569 |
Nt5dc1 | Zfp280c | ENSMUSP00000047126 | ENSMUSP00000075933 | 5'-nucleotidase domain-containing protein 1. | Zinc finger protein 280C; May function as a transcription factor. | 0.498 |
Pnma3 | Zfp280c | ENSMUSP00000054177 | ENSMUSP00000075933 | Paraneoplastic antigen Ma3 homolog; Belongs to the PNMA family. | Zinc finger protein 280C; May function as a transcription factor. | 0.552 |
Siae | Zfp280c | ENSMUSP00000149505 | ENSMUSP00000075933 | Sialate O-acetylesterase large subunit; Catalyzes the removal of O-acetyl ester groups from position 9 of the parent sialic acid, N-acetylneuraminic acid. | Zinc finger protein 280C; May function as a transcription factor. | 0.477 |
Zfp280c | 4833439L19Rik | ENSMUSP00000075933 | ENSMUSP00000026989 | Zinc finger protein 280C; May function as a transcription factor. | Putative monooxygenase p33MONOX; Potential NADPH-dependent oxidoreductase. May be involved in the regulation of neuronal survival, differentiation and axonal outgrowth (By similarity). | 0.552 |
Zfp280c | Adnp2 | ENSMUSP00000075933 | ENSMUSP00000068560 | Zinc finger protein 280C; May function as a transcription factor. | Activity-dependent neuroprotector homeobox protein 2; May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.523 |