Defa38 protein (mouse) - STRING interaction network

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Predicted Interactions

gene neighborhood

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textmining

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[Homology]

Score

Defa38

Defensin, alpha, 38. (116 aa)

Predicted Functional Partners:

Cd4

0.499

Defa17

0.471

Defa35

0.465

Defa30

0.465

Defa32

0.464

Defa39

0.462

Defb18

0.461

Defa37

0.457

Defa43

0.457

Defb1

0.456

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cd4	Defa17	ENSMUSP00000024044	ENSMUSP00000078485	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.	0.520
Cd4	Defa30	ENSMUSP00000024044	ENSMUSP00000096497	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Defensin, alpha, 30.	0.499
Cd4	Defa32	ENSMUSP00000024044	ENSMUSP00000081054	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Alpha-defensin 20; May have microbicidal activities; Belongs to the alpha-defensin family.	0.520
Cd4	Defa35	ENSMUSP00000024044	ENSMUSP00000077259	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Alpha-defensin 5; Probably contributes to the antimicrobial barrier function of the small bowel mucosa; Belongs to the alpha-defensin family.	0.712
Cd4	Defa37	ENSMUSP00000024044	ENSMUSP00000081053	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Defensin, alpha, 36.	0.499
Cd4	Defa38	ENSMUSP00000024044	ENSMUSP00000076665	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Defensin, alpha, 38.	0.499
Cd4	Defa39	ENSMUSP00000024044	ENSMUSP00000071783	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Defensin, alpha, 39.	0.499
Cd4	Defa43	ENSMUSP00000024044	ENSMUSP00000106377	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	Defensin, alpha, 42.	0.499
Defa17	Cd4	ENSMUSP00000078485	ENSMUSP00000024044	Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.520
Defa17	Defa30	ENSMUSP00000078485	ENSMUSP00000096497	Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.	Defensin, alpha, 30.	0.462
Defa17	Defa32	ENSMUSP00000078485	ENSMUSP00000081054	Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.	Alpha-defensin 20; May have microbicidal activities; Belongs to the alpha-defensin family.	0.464
Defa17	Defa35	ENSMUSP00000078485	ENSMUSP00000077259	Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.	Alpha-defensin 5; Probably contributes to the antimicrobial barrier function of the small bowel mucosa; Belongs to the alpha-defensin family.	0.460
Defa17	Defa37	ENSMUSP00000078485	ENSMUSP00000081053	Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.	Defensin, alpha, 36.	0.479
Defa17	Defa38	ENSMUSP00000078485	ENSMUSP00000076665	Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.	Defensin, alpha, 38.	0.471
Defa17	Defa39	ENSMUSP00000078485	ENSMUSP00000071783	Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.	Defensin, alpha, 39.	0.472
Defa17	Defa43	ENSMUSP00000078485	ENSMUSP00000106377	Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.	Defensin, alpha, 42.	0.455
Defa17	Defb1	ENSMUSP00000078485	ENSMUSP00000051754	Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.	Beta-defensin 1; Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility; Belongs to the beta-defensin family.	0.561
Defa17	Defb18	ENSMUSP00000078485	ENSMUSP00000095427	Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.	Beta-defensin 18; Has antibacterial activity; Belongs to the beta-defensin family.	0.450
Defa30	Cd4	ENSMUSP00000096497	ENSMUSP00000024044	Defensin, alpha, 30.	T-cell surface glycoprotein CD4; Integral membrane glycoprotein that plays an essential role in the immune response and serves multiple functions in responses against both external and internal offenses. In T-cells, functions primarily as a coreceptor for MHC class II molecule:peptide complex. The antigens presented by class II peptides are derived from extracellular proteins while class I peptides are derived from cytosolic proteins. Interacts simultaneously with the T-cell receptor (TCR) and the MHC class II presented by antigen presenting cells (APCs). In turn, recruits the Src kina [...]	0.499
Defa30	Defa17	ENSMUSP00000096497	ENSMUSP00000078485	Defensin, alpha, 30.	Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.	0.462