node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Clk1 | Clk2 | ENSMUSP00000034868 | ENSMUSP00000113390 | Dual specificity protein kinase CLK1; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA. | Dual specificity protein kinase CLK2; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphor [...] | 0.534 |
Clk1 | Rsrp1 | ENSMUSP00000034868 | ENSMUSP00000077226 | Dual specificity protein kinase CLK1; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA. | Arginine/serine-rich protein 1; Belongs to the RSRP family. | 0.555 |
Clk1 | Srsf5 | ENSMUSP00000034868 | ENSMUSP00000105980 | Dual specificity protein kinase CLK1; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA. | Serine/arginine-rich splicing factor 5; May be required for progression through G1 and entry into S phase of cell growth. May play a regulatory role in pre-mRNA splicing. Autoregulates its own expression. Plays a role in constitutive splicing and can modulate the selection of alternative splice sites (By similarity); Belongs to the splicing factor SR family. | 0.571 |
Clk2 | Clk1 | ENSMUSP00000113390 | ENSMUSP00000034868 | Dual specificity protein kinase CLK2; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphor [...] | Dual specificity protein kinase CLK1; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA. | 0.534 |
Clk2 | Clk3 | ENSMUSP00000113390 | ENSMUSP00000067341 | Dual specificity protein kinase CLK2; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphor [...] | Dual specificity protein kinase CLK3; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre- mRNA in endothelial cells; Belongs to the protein kinase superfamily. CMGC Se [...] | 0.598 |
Clk2 | Rsrp1 | ENSMUSP00000113390 | ENSMUSP00000077226 | Dual specificity protein kinase CLK2; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphor [...] | Arginine/serine-rich protein 1; Belongs to the RSRP family. | 0.560 |
Clk3 | Clk2 | ENSMUSP00000067341 | ENSMUSP00000113390 | Dual specificity protein kinase CLK3; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre- mRNA in endothelial cells; Belongs to the protein kinase superfamily. CMGC Se [...] | Dual specificity protein kinase CLK2; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphor [...] | 0.598 |
Clk3 | Rsrp1 | ENSMUSP00000067341 | ENSMUSP00000077226 | Dual specificity protein kinase CLK3; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre- mRNA in endothelial cells; Belongs to the protein kinase superfamily. CMGC Se [...] | Arginine/serine-rich protein 1; Belongs to the RSRP family. | 0.534 |
Clk3 | Srsf5 | ENSMUSP00000067341 | ENSMUSP00000105980 | Dual specificity protein kinase CLK3; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre- mRNA in endothelial cells; Belongs to the protein kinase superfamily. CMGC Se [...] | Serine/arginine-rich splicing factor 5; May be required for progression through G1 and entry into S phase of cell growth. May play a regulatory role in pre-mRNA splicing. Autoregulates its own expression. Plays a role in constitutive splicing and can modulate the selection of alternative splice sites (By similarity); Belongs to the splicing factor SR family. | 0.444 |
Fam90a1b-2 | Rsrp1 | ENSMUSP00000158935 | ENSMUSP00000077226 | Uncharacterized protein. | Arginine/serine-rich protein 1; Belongs to the RSRP family. | 0.643 |
Klhl28 | Rsrp1 | ENSMUSP00000152602 | ENSMUSP00000077226 | Kelch-like protein 28. | Arginine/serine-rich protein 1; Belongs to the RSRP family. | 0.568 |
Rhd | Rsrp1 | ENSMUSP00000030627 | ENSMUSP00000077226 | Blood group Rh(D) polypeptide; May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. | Arginine/serine-rich protein 1; Belongs to the RSRP family. | 0.471 |
Rhd | Tmem50a | ENSMUSP00000030627 | ENSMUSP00000030626 | Blood group Rh(D) polypeptide; May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. | Transmembrane protein 50A. | 0.463 |
Rsrp1 | Clk1 | ENSMUSP00000077226 | ENSMUSP00000034868 | Arginine/serine-rich protein 1; Belongs to the RSRP family. | Dual specificity protein kinase CLK1; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex and may be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing. Phosphorylates: SRSF1, SRSF3 and PTPN1. Regulates the alternative splicing of tissue factor (F3) pre-mRNA in endothelial cells and adenovirus E1A pre-mRNA. | 0.555 |
Rsrp1 | Clk2 | ENSMUSP00000077226 | ENSMUSP00000113390 | Arginine/serine-rich protein 1; Belongs to the RSRP family. | Dual specificity protein kinase CLK2; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Acts as a suppressor of hepatic gluconeogenesis and glucose output by repressing PPARGC1A transcriptional activity on gluconeogenic genes via its phosphorylation. Phosphor [...] | 0.560 |
Rsrp1 | Clk3 | ENSMUSP00000077226 | ENSMUSP00000067341 | Arginine/serine-rich protein 1; Belongs to the RSRP family. | Dual specificity protein kinase CLK3; Dual specificity kinase acting on both serine/threonine and tyrosine-containing substrates. Phosphorylates serine- and arginine- rich (SR) proteins of the spliceosomal complex. May be a constituent of a network of regulatory mechanisms that enable SR proteins to control RNA splicing and can cause redistribution of SR proteins from speckles to a diffuse nucleoplasmic distribution. Phosphorylates SRSF1 and SRSF3. Regulates the alternative splicing of tissue factor (F3) pre- mRNA in endothelial cells; Belongs to the protein kinase superfamily. CMGC Se [...] | 0.534 |
Rsrp1 | Fam90a1b-2 | ENSMUSP00000077226 | ENSMUSP00000158935 | Arginine/serine-rich protein 1; Belongs to the RSRP family. | Uncharacterized protein. | 0.643 |
Rsrp1 | Klhl28 | ENSMUSP00000077226 | ENSMUSP00000152602 | Arginine/serine-rich protein 1; Belongs to the RSRP family. | Kelch-like protein 28. | 0.568 |
Rsrp1 | Rhd | ENSMUSP00000077226 | ENSMUSP00000030627 | Arginine/serine-rich protein 1; Belongs to the RSRP family. | Blood group Rh(D) polypeptide; May be part of an oligomeric complex which is likely to have a transport or channel function in the erythrocyte membrane. | 0.471 |
Rsrp1 | Srsf5 | ENSMUSP00000077226 | ENSMUSP00000105980 | Arginine/serine-rich protein 1; Belongs to the RSRP family. | Serine/arginine-rich splicing factor 5; May be required for progression through G1 and entry into S phase of cell growth. May play a regulatory role in pre-mRNA splicing. Autoregulates its own expression. Plays a role in constitutive splicing and can modulate the selection of alternative splice sites (By similarity); Belongs to the splicing factor SR family. | 0.794 |