STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Mrpl1839S ribosomal protein L18, mitochondrial; Together with thiosulfate sulfurtransferase (TST), acts as a mitochondrial import factor for the cytosolic 5S rRNA. The precursor form shows RNA chaperone activity; is able to fold the 5S rRNA into an import-competent conformation that is recognized by rhodanese (TST). Both the cytoplasmic and mitochondrial forms are able to bind to the helix IV-loop D in the gamma domain of the 5S rRNA (By similarity). (180 aa)    
Predicted Functional Partners:
Mrpl44
39S ribosomal protein L44, mitochondrial; Component of the 39S subunit of mitochondrial ribosome. May have a function in the assembly/stability of nascent mitochondrial polypeptides exiting the ribosome; Belongs to the ribonuclease III family. Mitochondrion- specific ribosomal protein mL44 subfamily.
   
 
 0.949
Mrpl40
39S ribosomal protein L40, mitochondrial.
   
   0.942
Mrpl58
Peptidyl-tRNA hydrolase ICT1, mitochondrial; Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes (By similarity).
   
   0.938
Mrps25
28S ribosomal protein S25, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mS25 family.
   
 
 0.935
Mrps30
28S ribosomal protein S30, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL65 family.
   
   0.930
Mrpl15
39S ribosomal protein L15, mitochondrial.
   
 
 0.930
Mrps10
28S ribosomal protein S10, mitochondrial; Belongs to the universal ribosomal protein uS10 family.
   
 
 0.922
Mrpl49
39S ribosomal protein L49, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL49 family.
   
   0.916
Mrpl32
39S ribosomal protein L32, mitochondrial; Belongs to the bacterial ribosomal protein bL32 family.
   
   0.913
Mrpl45
39S ribosomal protein L45, mitochondrial; Belongs to the mitochondrion-specific ribosomal protein mL45 family.
   
   0.909
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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