node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bola1 | Plekhb1 | ENSMUSP00000102716 | ENSMUSP00000078175 | BolA-like protein 1; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity). | Pleckstrin homology domain-containing family B member 1. | 0.506 |
Cckbr | Plekhb1 | ENSMUSP00000033189 | ENSMUSP00000078175 | Gastrin/cholecystokinin type B receptor; Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). Belongs to the G-protein coupled receptor 1 family. | Pleckstrin homology domain-containing family B member 1. | 0.432 |
Gnat1 | Plekhb1 | ENSMUSP00000010205 | ENSMUSP00000078175 | Guanine nucleotide-binding protein G(t) subunit alpha-1; Functions as signal transducer for the rod photoreceptor RHO. Required for normal RHO-mediated light perception by the retina (By similarity). Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs), such as the photoreceptor RHO. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Activated RHO promotes GDP release and GTP binding. Signaling is mediated via downstream eff [...] | Pleckstrin homology domain-containing family B member 1. | 0.480 |
Heca | Plekhb1 | ENSMUSP00000040707 | ENSMUSP00000078175 | Hdc homolog, cell cycle regulator. | Pleckstrin homology domain-containing family B member 1. | 0.538 |
Mxd3 | Plekhb1 | ENSMUSP00000021941 | ENSMUSP00000078175 | Max dimerization protein 3; Transcriptional repressor. Binds with MAX to form a sequence- specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation. | Pleckstrin homology domain-containing family B member 1. | 0.437 |
Mxd3 | Syngr4 | ENSMUSP00000021941 | ENSMUSP00000047035 | Max dimerization protein 3; Transcriptional repressor. Binds with MAX to form a sequence- specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation. | Synaptogyrin-4. | 0.496 |
Mxd3 | Tex26 | ENSMUSP00000021941 | ENSMUSP00000143851 | Max dimerization protein 3; Transcriptional repressor. Binds with MAX to form a sequence- specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation. | Testis-expressed protein 26. | 0.559 |
Plekhb1 | Bola1 | ENSMUSP00000078175 | ENSMUSP00000102716 | Pleckstrin homology domain-containing family B member 1. | BolA-like protein 1; Acts as a mitochondrial iron-sulfur (Fe-S) cluster assembly factor that facilitates (Fe-S) cluster insertion into a subset of mitochondrial proteins (By similarity). Probably acts together with the monothiol glutaredoxin GLRX5. May protect cells against oxidative stress (By similarity). | 0.506 |
Plekhb1 | Cckbr | ENSMUSP00000078175 | ENSMUSP00000033189 | Pleckstrin homology domain-containing family B member 1. | Gastrin/cholecystokinin type B receptor; Receptor for gastrin and cholecystokinin. The CCK-B receptors occur throughout the central nervous system where they modulate anxiety, analgesia, arousal, and neuroleptic activity. This receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system (By similarity). Belongs to the G-protein coupled receptor 1 family. | 0.432 |
Plekhb1 | Gnat1 | ENSMUSP00000078175 | ENSMUSP00000010205 | Pleckstrin homology domain-containing family B member 1. | Guanine nucleotide-binding protein G(t) subunit alpha-1; Functions as signal transducer for the rod photoreceptor RHO. Required for normal RHO-mediated light perception by the retina (By similarity). Guanine nucleotide-binding proteins (G proteins) function as transducers downstream of G protein-coupled receptors (GPCRs), such as the photoreceptor RHO. The alpha chain contains the guanine nucleotide binding site and alternates between an active, GTP-bound state and an inactive, GDP-bound state. Activated RHO promotes GDP release and GTP binding. Signaling is mediated via downstream eff [...] | 0.480 |
Plekhb1 | Heca | ENSMUSP00000078175 | ENSMUSP00000040707 | Pleckstrin homology domain-containing family B member 1. | Hdc homolog, cell cycle regulator. | 0.538 |
Plekhb1 | Mxd3 | ENSMUSP00000078175 | ENSMUSP00000021941 | Pleckstrin homology domain-containing family B member 1. | Max dimerization protein 3; Transcriptional repressor. Binds with MAX to form a sequence- specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation. | 0.437 |
Plekhb1 | Prl3b1 | ENSMUSP00000078175 | ENSMUSP00000047680 | Pleckstrin homology domain-containing family B member 1. | Prolactin-3B1; Belongs to the somatotropin/prolactin family. | 0.446 |
Plekhb1 | Shank1 | ENSMUSP00000078175 | ENSMUSP00000103571 | Pleckstrin homology domain-containing family B member 1. | SH3 and multiple ankyrin repeat domains protein 1; Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction. Overexpression promotes maturation of dendritic spines and the enlargement of spine heads via its ability to recruit Homer to postsynaptic sites, and enhances presynaptic function (By similarity); B [...] | 0.502 |
Plekhb1 | Syngr4 | ENSMUSP00000078175 | ENSMUSP00000047035 | Pleckstrin homology domain-containing family B member 1. | Synaptogyrin-4. | 0.753 |
Plekhb1 | Tex26 | ENSMUSP00000078175 | ENSMUSP00000143851 | Pleckstrin homology domain-containing family B member 1. | Testis-expressed protein 26. | 0.650 |
Plekhb1 | Wdr25 | ENSMUSP00000078175 | ENSMUSP00000035553 | Pleckstrin homology domain-containing family B member 1. | WD repeat-containing protein 25. | 0.424 |
Prl3b1 | Plekhb1 | ENSMUSP00000047680 | ENSMUSP00000078175 | Prolactin-3B1; Belongs to the somatotropin/prolactin family. | Pleckstrin homology domain-containing family B member 1. | 0.446 |
Shank1 | Plekhb1 | ENSMUSP00000103571 | ENSMUSP00000078175 | SH3 and multiple ankyrin repeat domains protein 1; Seems to be an adapter protein in the postsynaptic density (PSD) of excitatory synapses that interconnects receptors of the postsynaptic membrane including NMDA-type and metabotropic glutamate receptors, and the actin-based cytoskeleton. Plays a role in the structural and functional organization of the dendritic spine and synaptic junction. Overexpression promotes maturation of dendritic spines and the enlargement of spine heads via its ability to recruit Homer to postsynaptic sites, and enhances presynaptic function (By similarity); B [...] | Pleckstrin homology domain-containing family B member 1. | 0.502 |
Syngr4 | Mxd3 | ENSMUSP00000047035 | ENSMUSP00000021941 | Synaptogyrin-4. | Max dimerization protein 3; Transcriptional repressor. Binds with MAX to form a sequence- specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. Antagonizes MYC transcriptional activity by competing for MAX and suppresses MYC dependent cell transformation. | 0.496 |