node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arl2bp | Eaf1 | ENSMUSP00000034228 | ENSMUSP00000022446 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | 0.485 |
Arl2bp | Efcab1 | ENSMUSP00000034228 | ENSMUSP00000087744 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | EF-hand calcium-binding domain-containing protein 1. | 0.537 |
Arl2bp | Gpatch3 | ENSMUSP00000034228 | ENSMUSP00000030662 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6. | 0.555 |
Arl2bp | Plekha8 | ENSMUSP00000034228 | ENSMUSP00000112466 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | Pleckstrin homology domain-containing family A member 8; Cargo transport protein that is required for apical transport from the trans-Golgi network (TGN). Transports AQP2 from the trans- Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non- vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation [...] | 0.506 |
Arl2bp | Rspry1 | ENSMUSP00000034228 | ENSMUSP00000057275 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | RING finger and SPRY domain-containing protein 1. | 0.655 |
Arl2bp | Znrf2 | ENSMUSP00000034228 | ENSMUSP00000078795 | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | E3 ubiquitin-protein ligase ZNRF2; May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | 0.517 |
Eaf1 | Arl2bp | ENSMUSP00000022446 | ENSMUSP00000034228 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | 0.485 |
Eaf1 | Efcab1 | ENSMUSP00000022446 | ENSMUSP00000087744 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | EF-hand calcium-binding domain-containing protein 1. | 0.626 |
Eaf1 | Gpatch3 | ENSMUSP00000022446 | ENSMUSP00000030662 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6. | 0.654 |
Eaf1 | Plekha8 | ENSMUSP00000022446 | ENSMUSP00000112466 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | Pleckstrin homology domain-containing family A member 8; Cargo transport protein that is required for apical transport from the trans-Golgi network (TGN). Transports AQP2 from the trans- Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non- vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation [...] | 0.465 |
Eaf1 | Rspry1 | ENSMUSP00000022446 | ENSMUSP00000057275 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | RING finger and SPRY domain-containing protein 1. | 0.667 |
Eaf1 | Znrf2 | ENSMUSP00000022446 | ENSMUSP00000078795 | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | E3 ubiquitin-protein ligase ZNRF2; May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | 0.566 |
Efcab1 | Arl2bp | ENSMUSP00000087744 | ENSMUSP00000034228 | EF-hand calcium-binding domain-containing protein 1. | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | 0.537 |
Efcab1 | Eaf1 | ENSMUSP00000087744 | ENSMUSP00000022446 | EF-hand calcium-binding domain-containing protein 1. | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | 0.626 |
Efcab1 | Gpatch3 | ENSMUSP00000087744 | ENSMUSP00000030662 | EF-hand calcium-binding domain-containing protein 1. | G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6. | 0.667 |
Efcab1 | Plekha8 | ENSMUSP00000087744 | ENSMUSP00000112466 | EF-hand calcium-binding domain-containing protein 1. | Pleckstrin homology domain-containing family A member 8; Cargo transport protein that is required for apical transport from the trans-Golgi network (TGN). Transports AQP2 from the trans- Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non- vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation [...] | 0.516 |
Efcab1 | Rspry1 | ENSMUSP00000087744 | ENSMUSP00000057275 | EF-hand calcium-binding domain-containing protein 1. | RING finger and SPRY domain-containing protein 1. | 0.687 |
Efcab1 | Znrf2 | ENSMUSP00000087744 | ENSMUSP00000078795 | EF-hand calcium-binding domain-containing protein 1. | E3 ubiquitin-protein ligase ZNRF2; May play a role in the establishment and maintenance of neuronal transmission and plasticity via its ubiquitin ligase activity. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates. | 0.557 |
Gpatch3 | Arl2bp | ENSMUSP00000030662 | ENSMUSP00000034228 | G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6. | ADP-ribosylation factor-like protein 2-binding protein; Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2 (By similarity). | 0.555 |
Gpatch3 | Eaf1 | ENSMUSP00000030662 | ENSMUSP00000022446 | G patch domain-containing protein 3; Involved in transcriptional regulation. It is able to activate transcription from CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development. Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6. | ELL-associated factor 1; Acts as a transcriptional transactivator of ELL and ELL2 elongation activities. | 0.654 |