node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Abhd17a | Scamp4 | ENSMUSP00000003436 | ENSMUSP00000078808 | Alpha/beta hydrolase domain-containing protein 17A; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards NRAS. Has depalmitoylating activity towards DLG4/PSD95. May have depalmitoylating activity towars MAP6. | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | 0.522 |
Anp32b | Scamp4 | ENSMUSP00000099990 | ENSMUSP00000078808 | Acidic leucine-rich nuclear phosphoprotein 32 family member B; Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome (By similarity); Belongs to the ANP32 family. | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | 0.461 |
Dus3l | Rexo1 | ENSMUSP00000007747 | ENSMUSP00000049705 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. | RNA exonuclease 1 homolog; Seems to have no detectable effect on transcription elongation in vitro. | 0.573 |
Dus3l | Scamp4 | ENSMUSP00000007747 | ENSMUSP00000078808 | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | 0.555 |
Dync1i1 | Dync1i2 | ENSMUSP00000111221 | ENSMUSP00000107768 | Cytoplasmic dynein 1 intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kine [...] | Cytoplasmic dynein 1 intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes (By similarity). | 0.955 |
Dync1i1 | Scamp4 | ENSMUSP00000111221 | ENSMUSP00000078808 | Cytoplasmic dynein 1 intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kine [...] | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | 0.425 |
Dync1i2 | Dync1i1 | ENSMUSP00000107768 | ENSMUSP00000111221 | Cytoplasmic dynein 1 intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes (By similarity). | Cytoplasmic dynein 1 intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kine [...] | 0.955 |
Dync1i2 | Scamp4 | ENSMUSP00000107768 | ENSMUSP00000078808 | Cytoplasmic dynein 1 intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes (By similarity). | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | 0.507 |
Epcam | Scamp4 | ENSMUSP00000061935 | ENSMUSP00000078808 | Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family. | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | 0.405 |
Fam174b | Scamp4 | ENSMUSP00000103080 | ENSMUSP00000078808 | Membrane protein FAM174B; Essential for Golgi structural integrity. Belongs to the FAM174 family. | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | 0.468 |
Fam174b | Xxylt1 | ENSMUSP00000103080 | ENSMUSP00000050246 | Membrane protein FAM174B; Essential for Golgi structural integrity. Belongs to the FAM174 family. | Xyloside xylosyltransferase 1; Alpha-1,3-xylosyltransferase, which elongates the O-linked xylose-glucose disaccharide attached to EGF-like repeats in the extracellular domain of target proteins by catalyzing the addition of the second xylose. Known targets include Notch proteins and coagulation factors, such as F9. | 0.517 |
Nf2 | Scamp4 | ENSMUSP00000105536 | ENSMUSP00000078808 | Merlin; Probable regulator of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway, a signaling pathway that plays a pivotal role in tumor suppression by restricting proliferation and promoting apoptosis. Along with WWC1 can synergistically induce the phosphorylation of LATS1 and LATS2 and can probably function in the regulation of the Hippo/SWH (Sav/Wts/Hpo) signaling pathway. May act as a membrane stabilizing protein. May inhibit PI3 kinase by binding to AGAP2 and impairing its stimulating activity. Suppresses cell proliferation and tumorigenesis by inhibiting the CUL4A-RBX1-DDB1-VprBP/DCAF [...] | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | 0.489 |
Rexo1 | Dus3l | ENSMUSP00000049705 | ENSMUSP00000007747 | RNA exonuclease 1 homolog; Seems to have no detectable effect on transcription elongation in vitro. | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. | 0.573 |
Rexo1 | Scamp4 | ENSMUSP00000049705 | ENSMUSP00000078808 | RNA exonuclease 1 homolog; Seems to have no detectable effect on transcription elongation in vitro. | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | 0.541 |
Scamp4 | Abhd17a | ENSMUSP00000078808 | ENSMUSP00000003436 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | Alpha/beta hydrolase domain-containing protein 17A; Hydrolyzes fatty acids from S-acylated cysteine residues in proteins. Has depalmitoylating activity towards NRAS. Has depalmitoylating activity towards DLG4/PSD95. May have depalmitoylating activity towars MAP6. | 0.522 |
Scamp4 | Anp32b | ENSMUSP00000078808 | ENSMUSP00000099990 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | Acidic leucine-rich nuclear phosphoprotein 32 family member B; Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S phase. Anti-apoptotic protein which functions as a caspase-3 inhibitor. Has no phosphatase 2A (PP2A) inhibitor activity. Exhibits histone chaperone properties, stimulating core histones to assemble into a nucleosome (By similarity); Belongs to the ANP32 family. | 0.461 |
Scamp4 | Dus3l | ENSMUSP00000078808 | ENSMUSP00000007747 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | tRNA-dihydrouridine(47) synthase [NAD(P)(+)]-like; Catalyzes the synthesis of dihydrouridine, a modified base found in the D-loop of most tRNAs. | 0.555 |
Scamp4 | Dync1i1 | ENSMUSP00000078808 | ENSMUSP00000111221 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | Cytoplasmic dynein 1 intermediate chain 1; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. May play a role in mediating the interaction of cytoplasmic dynein with membranous organelles and kine [...] | 0.425 |
Scamp4 | Dync1i2 | ENSMUSP00000078808 | ENSMUSP00000107768 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | Cytoplasmic dynein 1 intermediate chain 2; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes (By similarity). | 0.507 |
Scamp4 | Epcam | ENSMUSP00000078808 | ENSMUSP00000061935 | Secretory carrier-associated membrane protein 4; Probably involved in membrane protein trafficking. Belongs to the SCAMP family. | Epithelial cell adhesion molecule; May act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. Plays a role in embryonic stem cells proliferation and differentiation. Up-regulates the expression of FABP5, MYC and cyclins A and E (By similarity). Belongs to the EPCAM family. | 0.405 |