STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Defa24Alpha-defensin 24; May have microbicidal activities; Belongs to the alpha-defensin family. (93 aa)    
Predicted Functional Partners:
Defa17
Alpha-defensin 3; Probably contributes to the antimicrobial barrier function of the small bowel mucosa.
   
 
0.885
Defa26
Alpha-defensin 26; May have microbicidal activities; Belongs to the alpha-defensin family.
   
 
0.879
Defa3
Defensin, alpha, 3.
   
  
0.819
Defa23
Defensin, alpha, 23.
   
  
0.818
Defa22
Alpha-defensin 22.
   
  
0.814
Defa5
Alpha-defensin 5.
   
  
0.792
Defa21
Alpha-defensin 21; May have microbicidal activities; Belongs to the alpha-defensin family.
   
 
0.759
Defa20
Defensin, alpha, 20.
   
  
0.692
Lyz1
Lysozyme C-1; Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Lyz1 is active against a range of Gram-positive and Gram-negative bacteria. Less effective than Lyz2 in killing Gram-negative bacteria. Lyz1 and Lyz2 are equally effective in killing Gram-positive bacteria; Belongs to the glycosyl hydrolase 22 family.
   
  
 0.610
Mptx2
Pentaxin.
   
    0.601
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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