node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Brix1 | Ebna1bp2 | ENSMUSP00000022855 | ENSMUSP00000030501 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | 0.999 |
Brix1 | Mak16 | ENSMUSP00000022855 | ENSMUSP00000033983 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Protein MAK16 homolog. | 0.988 |
Brix1 | Mrto4 | ENSMUSP00000022855 | ENSMUSP00000099561 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.990 |
Brix1 | Pes1 | ENSMUSP00000022855 | ENSMUSP00000020705 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.989 |
Brix1 | Ppan | ENSMUSP00000022855 | ENSMUSP00000004203 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Suppressor of SWI4 1 homolog; May have a role in cell growth. | 0.928 |
Brix1 | Rpf1 | ENSMUSP00000022855 | ENSMUSP00000029838 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome production factor 1; May be required for ribosome biogenesis. | 0.997 |
Brix1 | Rrp1b | ENSMUSP00000022855 | ENSMUSP00000080085 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosomal RNA processing protein 1 homolog B; Positively regulates DNA damage-induced apoptosis by acting as a transcriptional coactivator of proapoptotic target genes of the transcriptional activator E2F1 (By similarity). Likely to play a role in ribosome biogenesis by targeting serine/threonine protein phosphatase PP1 to the nucleolus (By similarity). Involved in regulation of mRNA splicing. Inhibits SIPA1 GTPase activity. Involved in regulating expression of extracellular matrix genes. Associates with chromatin and may play a role in modulating chromatin structure (By similarity). B [...] | 0.974 |
Brix1 | Wdr12 | ENSMUSP00000022855 | ENSMUSP00000027173 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.993 |
Brix1 | Wdr74 | ENSMUSP00000022855 | ENSMUSP00000043315 | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | WD repeat-containing protein 74; Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (By similarity). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development. | 0.977 |
Ebna1bp2 | Brix1 | ENSMUSP00000030501 | ENSMUSP00000022855 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | 0.999 |
Ebna1bp2 | Mak16 | ENSMUSP00000030501 | ENSMUSP00000033983 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Protein MAK16 homolog. | 0.994 |
Ebna1bp2 | Mrto4 | ENSMUSP00000030501 | ENSMUSP00000099561 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | mRNA turnover protein 4 homolog; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. | 0.994 |
Ebna1bp2 | Pes1 | ENSMUSP00000030501 | ENSMUSP00000020705 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Pescadillo homolog; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome; Belongs to the pescadillo family. | 0.999 |
Ebna1bp2 | Ppan | ENSMUSP00000030501 | ENSMUSP00000004203 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Suppressor of SWI4 1 homolog; May have a role in cell growth. | 0.979 |
Ebna1bp2 | Rpf1 | ENSMUSP00000030501 | ENSMUSP00000029838 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome production factor 1; May be required for ribosome biogenesis. | 0.995 |
Ebna1bp2 | Rrp1b | ENSMUSP00000030501 | ENSMUSP00000080085 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosomal RNA processing protein 1 homolog B; Positively regulates DNA damage-induced apoptosis by acting as a transcriptional coactivator of proapoptotic target genes of the transcriptional activator E2F1 (By similarity). Likely to play a role in ribosome biogenesis by targeting serine/threonine protein phosphatase PP1 to the nucleolus (By similarity). Involved in regulation of mRNA splicing. Inhibits SIPA1 GTPase activity. Involved in regulating expression of extracellular matrix genes. Associates with chromatin and may play a role in modulating chromatin structure (By similarity). B [...] | 0.986 |
Ebna1bp2 | Wdr12 | ENSMUSP00000030501 | ENSMUSP00000027173 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome. | 0.993 |
Ebna1bp2 | Wdr74 | ENSMUSP00000030501 | ENSMUSP00000043315 | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | WD repeat-containing protein 74; Regulatory protein of the MTREX-exosome complex involved in the synthesis of the 60S ribosomal subunit. Participates in an early cleavage of the pre-rRNA processing pathway in cooperation with NVL (By similarity). Required for blastocyst formation, is necessary for RNA transcription, processing and/or stability during preimplantation development. | 0.992 |
Mak16 | Brix1 | ENSMUSP00000033983 | ENSMUSP00000022855 | Protein MAK16 homolog. | Ribosome biogenesis protein BRX1 homolog; Required for biogenesis of the 60S ribosomal subunit. Belongs to the BRX1 family. | 0.988 |
Mak16 | Ebna1bp2 | ENSMUSP00000033983 | ENSMUSP00000030501 | Protein MAK16 homolog. | Probable rRNA-processing protein EBP2; Required for the processing of the 27S pre-rRNA. | 0.994 |