Zdhhc12 protein (mouse) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

Zdhhc12

Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family. (281 aa)

Predicted Functional Partners:

Zdhhc22

0.638

Zdhhc24

0.608

Zfp28

0.581

Ankrd9

0.461

Ppt2

0.437

Gphn

0.427

Zdhhc13

0.419

Ppt1

0.416

Your Current Organism:

Mus musculus

NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Ankrd9	Zdhhc12	ENSMUSP00000120816	ENSMUSP00000080521	Ankyrin repeat domain-containing protein 9.	Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family.	0.461
Gphn	Zdhhc12	ENSMUSP00000106018	ENSMUSP00000080521	Molybdopterin molybdenumtransferase; Microtubule-associated protein involved in membrane protein- cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. In the C-terminal section; belongs to the MoeA family.	Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family.	0.427
Ppt1	Ppt2	ENSMUSP00000030412	ENSMUSP00000131243	Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.	Lysosomal thioesterase PPT2; Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins (By similarity).	0.931
Ppt1	Zdhhc12	ENSMUSP00000030412	ENSMUSP00000080521	Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.	Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family.	0.416
Ppt1	Zdhhc13	ENSMUSP00000030412	ENSMUSP00000112498	Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.	Palmitoyltransferase ZDHHC13; Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.	0.636
Ppt1	Zdhhc24	ENSMUSP00000030412	ENSMUSP00000006632	Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.	Probable palmitoyltransferase ZDHHC24.	0.564
Ppt2	Ppt1	ENSMUSP00000131243	ENSMUSP00000030412	Lysosomal thioesterase PPT2; Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins (By similarity).	Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.	0.931
Ppt2	Zdhhc12	ENSMUSP00000131243	ENSMUSP00000080521	Lysosomal thioesterase PPT2; Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins (By similarity).	Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family.	0.437
Ppt2	Zdhhc13	ENSMUSP00000131243	ENSMUSP00000112498	Lysosomal thioesterase PPT2; Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins (By similarity).	Palmitoyltransferase ZDHHC13; Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.	0.574
Ppt2	Zdhhc24	ENSMUSP00000131243	ENSMUSP00000006632	Lysosomal thioesterase PPT2; Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins (By similarity).	Probable palmitoyltransferase ZDHHC24.	0.432
Zdhhc12	Ankrd9	ENSMUSP00000080521	ENSMUSP00000120816	Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family.	Ankyrin repeat domain-containing protein 9.	0.461
Zdhhc12	Gphn	ENSMUSP00000080521	ENSMUSP00000106018	Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family.	Molybdopterin molybdenumtransferase; Microtubule-associated protein involved in membrane protein- cytoskeleton interactions. It is thought to anchor the inhibitory glycine receptor (GLYR) to subsynaptic microtubules. Catalyzes two steps in the biosynthesis of the molybdenum cofactor. In the first step, molybdopterin is adenylated. Subsequently, molybdate is inserted into adenylated molybdopterin and AMP is released. In the C-terminal section; belongs to the MoeA family.	0.427
Zdhhc12	Ppt1	ENSMUSP00000080521	ENSMUSP00000030412	Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family.	Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.	0.416
Zdhhc12	Ppt2	ENSMUSP00000080521	ENSMUSP00000131243	Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family.	Lysosomal thioesterase PPT2; Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins (By similarity).	0.437
Zdhhc12	Zdhhc13	ENSMUSP00000080521	ENSMUSP00000112498	Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family.	Palmitoyltransferase ZDHHC13; Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.	0.419
Zdhhc12	Zdhhc22	ENSMUSP00000080521	ENSMUSP00000152660	Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family.	Palmitoyltransferase ZDHHC22; Palmitoyltransferase that mediates palmitoylation of KCNMA1, regulating localization of KCNMA1 to the plasma membrane (By similarity). Might also mediate palmitoylation of CNN3.	0.638
Zdhhc12	Zdhhc24	ENSMUSP00000080521	ENSMUSP00000006632	Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family.	Probable palmitoyltransferase ZDHHC24.	0.608
Zdhhc12	Zfp28	ENSMUSP00000080521	ENSMUSP00000079812	Probable palmitoyltransferase ZDHHC12; Belongs to the DHHC palmitoyltransferase family.	Zinc finger protein 28; May be involved in transcriptional regulation. May have a role in embryonic development.	0.581
Zdhhc13	Ppt1	ENSMUSP00000112498	ENSMUSP00000030412	Palmitoyltransferase ZDHHC13; Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.	Palmitoyl-protein thioesterase 1; Removes thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.	0.636
Zdhhc13	Ppt2	ENSMUSP00000112498	ENSMUSP00000131243	Palmitoyltransferase ZDHHC13; Palmitoyltransferase for HTT and GAD2. May play a role in Mg(2+) transport. Belongs to the DHHC palmitoyltransferase family. AKR/ZDHHC17 subfamily.	Lysosomal thioesterase PPT2; Removes thioester-linked fatty acyl groups from various substrates including S-palmitoyl-CoA. Has the highest S-thioesterase activity for the acyl groups palmitic and myristic acid followed by other short- and long-chain acyl substrates. However, because of structural constraints, is unable to remove palmitate from peptides or proteins (By similarity).	0.574