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Lamp3 protein (mouse) - STRING interaction network
"Lamp3" - Lysosome-associated membrane glycoprotein 3 in Mus musculus
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Lamp3Lysosome-associated membrane glycoprotein 3; May play a role in dendritic cell function and in adaptive immunity (411 aa)    
Predicted Functional Partners:
Cd83
CD83 antigen; May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation (196 aa)
     
   
  0.703
Cd207
C-type lectin domain family 4 member K; Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells (331 aa)
     
   
  0.612
Cd209a
CD209 antigen-like protein A; Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (238 aa)
     
   
  0.598
Cd1d1
Antigen-presenting glycoprotein CD1d1; Antigen-presenting protein that binds self and non-self glycolipids and presents them to T-cell receptors on natural killer T-cells (336 aa)
           
  0.572
Cd86
T-lymphocyte activation antigen CD86; Receptor involved in the costimulatory signal essential for T-lymphocyte proliferation and interleukin-2 production, by binding CD28 or CTLA-4. May play a critical role in the early events of T-cell activation and costimulation of naive T-cells, such as deciding between immunity and anergy that is made by T- cells within 24 hours after activation (309 aa)
     
   
  0.545
Ccr7
C-C chemokine receptor type 7; Receptor for the MIP-3-beta chemokine (378 aa)
     
   
  0.539
Cd80
T-lymphocyte activation antigen CD80; Involved in the costimulatory signal essential for T lymphocytes activation. T-cell proliferation and cytokine production is induced by the binding of CD28 or CTLA-4 to this receptor (306 aa)
     
   
  0.535
Cd209d
CD209 antigen-like protein D; Probable pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (237 aa)
     
   
  0.534
Cd209e
CD209 antigen-like protein E; Putative pathogen-recognition receptor. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments (208 aa)
     
   
  0.534
Cd209c
CD209 antigen-like protein C; Probable pathogen-recognition receptor. May recognize in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens (178 aa)
     
   
  0.533
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus muscaris, Mus musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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