node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Csmd3 | Fat3 | ENSMUSP00000098235 | ENSMUSP00000080808 | CUB and sushi domain-containing protein 3; Involved in dendrite development. | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | 0.645 |
Csmd3 | Zfhx4 | ENSMUSP00000098235 | ENSMUSP00000026284 | CUB and sushi domain-containing protein 3; Involved in dendrite development. | Zinc finger homeobox protein 4; May play a role in neural and muscle differentiation. May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.491 |
Cyfip1 | Fat3 | ENSMUSP00000032629 | ENSMUSP00000080808 | Cytoplasmic FMR1-interacting protein 1; Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E- FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with th [...] | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | 0.450 |
Dscam | Fat3 | ENSMUSP00000056040 | ENSMUSP00000080808 | Down syndrome cell adhesion molecule homolog; Cell adhesion molecule that plays a role in neuronal self- avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self- avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies. Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. Might also [...] | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | 0.426 |
Fat3 | Csmd3 | ENSMUSP00000080808 | ENSMUSP00000098235 | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | CUB and sushi domain-containing protein 3; Involved in dendrite development. | 0.645 |
Fat3 | Cyfip1 | ENSMUSP00000080808 | ENSMUSP00000032629 | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | Cytoplasmic FMR1-interacting protein 1; Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E- FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with th [...] | 0.450 |
Fat3 | Dscam | ENSMUSP00000080808 | ENSMUSP00000056040 | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | Down syndrome cell adhesion molecule homolog; Cell adhesion molecule that plays a role in neuronal self- avoidance. Promotes repulsion between specific neuronal processes of either the same cell or the same subtype of cells. Mediates within retinal amacrine and ganglion cell subtypes both isoneuronal self- avoidance for creating an orderly dendritic arborization and heteroneuronal self-avoidance to maintain the mosaic spacing between amacrine and ganglion cell bodies. Receptor for netrin required for axon guidance independently of and in collaboration with the receptor DCC. Might also [...] | 0.426 |
Fat3 | Fjx1 | ENSMUSP00000080808 | ENSMUSP00000097270 | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | Four-jointed box protein 1; Acts as an inhibitor of dendrite extension and branching. Belongs to the FJX1/FJ family. | 0.724 |
Fat3 | Lix1l | ENSMUSP00000080808 | ENSMUSP00000057623 | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | LIX1-like protein; Belongs to the LIX1 family. | 0.421 |
Fat3 | Mgat5b | ENSMUSP00000080808 | ENSMUSP00000099316 | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B; Glycosyltransferase that acts on alpha-linked mannose of N- glycans and O-mannosyl glycans. Catalyzes the transfer of N- acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6- linked mannose arms in the core structure of N-glycan (By similarity). Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adh [...] | 0.455 |
Fat3 | Pcdh1 | ENSMUSP00000080808 | ENSMUSP00000055199 | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | Protocadherin 1. | 0.456 |
Fat3 | Ssc4d | ENSMUSP00000080808 | ENSMUSP00000106782 | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | Scavenger receptor cysteine-rich domain-containing group B protein. | 0.499 |
Fat3 | Vasp | ENSMUSP00000080808 | ENSMUSP00000032561 | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | Vasodilator-stimulated phosphoprotein; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end [...] | 0.601 |
Fat3 | Zfhx4 | ENSMUSP00000080808 | ENSMUSP00000026284 | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | Zinc finger homeobox protein 4; May play a role in neural and muscle differentiation. May be involved in transcriptional regulation; Belongs to the krueppel C2H2-type zinc-finger protein family. | 0.469 |
Fjx1 | Fat3 | ENSMUSP00000097270 | ENSMUSP00000080808 | Four-jointed box protein 1; Acts as an inhibitor of dendrite extension and branching. Belongs to the FJX1/FJ family. | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | 0.724 |
Lix1l | Fat3 | ENSMUSP00000057623 | ENSMUSP00000080808 | LIX1-like protein; Belongs to the LIX1 family. | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | 0.421 |
Mgat5b | Fat3 | ENSMUSP00000099316 | ENSMUSP00000080808 | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B; Glycosyltransferase that acts on alpha-linked mannose of N- glycans and O-mannosyl glycans. Catalyzes the transfer of N- acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6- linked mannose arms in the core structure of N-glycan (By similarity). Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adh [...] | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | 0.455 |
Mgat5b | Pcdh1 | ENSMUSP00000099316 | ENSMUSP00000055199 | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B; Glycosyltransferase that acts on alpha-linked mannose of N- glycans and O-mannosyl glycans. Catalyzes the transfer of N- acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6- linked mannose arms in the core structure of N-glycan (By similarity). Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adh [...] | Protocadherin 1. | 0.480 |
Pcdh1 | Fat3 | ENSMUSP00000055199 | ENSMUSP00000080808 | Protocadherin 1. | Protocadherin Fat 3; May play a role in the interactions between neurites derived from specific subsets of neurons during development. | 0.456 |
Pcdh1 | Mgat5b | ENSMUSP00000055199 | ENSMUSP00000099316 | Protocadherin 1. | Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B; Glycosyltransferase that acts on alpha-linked mannose of N- glycans and O-mannosyl glycans. Catalyzes the transfer of N- acetylglucosamine (GlcNAc) to the beta 1-6 linkage of the mannose residue of GlcNAc-beta1,2-Man-alpha on both the alpha1,3- and alpha1,6- linked mannose arms in the core structure of N-glycan (By similarity). Also acts on the GlcNAc-beta1,2-Man-alpha1-Ser/Thr moiety, forming a 2,6-branched structure in brain O-mannosyl glycan. Plays an active role in modulating integrin and laminin-dependent adh [...] | 0.480 |