STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Nlrp14NACHT, LRR and PYD domains-containing protein 14; May be involved in inflammation and spermatogenesis. Belongs to the NLRP family. (993 aa)    
Predicted Functional Partners:
Oas1d
Inactive 2'-5'-oligoadenylate synthase 1D; Does not have 2'-5'-olygoadenylate synthetase activity, but can bind double-stranded RNA. May play a role in the control of female fertility, possibly by binding to and inhibiting OAS1A.
   
  
 0.574
Oas1h
2',5'-oligoadenylate synthetase-like 6.
   
  
 0.537
D5Ertd577e
DNA segment, Chr 5, ERATO Doi 577,-expressed.
   
  
 0.522
E330034G19Rik
RIKEN cDNA E330034G19 gene.
   
  
 0.513
Olfr976
Olfactory receptor MOR224-10.
   
  
 0.504
Padi6
Protein-arginine deiminase type-6; Catalyzes the deimination of arginine residues of proteins (By similarity). May be involved in cytoskeletal reorganization in the egg and early embryo.
   
  
 0.498
Gm2042
Predicted gene 2042.
   
  
 0.493
Oog1
Oogenesin-1; May act as a Ras-mediated signaling protein in early embryogenesis; Belongs to the PRAME family.
   
  
 0.471
Ooep
Oocyte-expressed protein homolog; As a member of the subcortical maternal complex (SCMC), plays an essential role for zygotes to progress beyond the first embryonic cell divisions.
   
  
 0.470
Cpsf4l
Cleavage and polyadenylation-specific factor 4-like.
   
  
 0.470
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.