node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Slc12a1 | Slc22a13 | ENSMUSP00000028630 | ENSMUSP00000081855 | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | Solute carrier family 22 member 13. | 0.552 |
Slc12a1 | Slc34a1 | ENSMUSP00000028630 | ENSMUSP00000153038 | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | Sodium-dependent phosphate transport protein 2A; Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx. | 0.830 |
Slc12a1 | Slc6a18 | ENSMUSP00000028630 | ENSMUSP00000152525 | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | Sodium-dependent neutral amino acid transporter B(0)AT3; Functions as a sodium and chloride-dependent neutral amino acid transporter in kidneys. Required CLTRN for cell surface expression and for its amino acid transporter activity. | 0.654 |
Slc12a1 | Tmem174 | ENSMUSP00000028630 | ENSMUSP00000057581 | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | Transmembrane protein 174. | 0.454 |
Slc17a1 | Slc22a13 | ENSMUSP00000006785 | ENSMUSP00000081855 | Sodium-dependent phosphate transport protein 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Plays a role in urate transport in the kidney; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. | Solute carrier family 22 member 13. | 0.496 |
Slc17a1 | Slc34a1 | ENSMUSP00000006785 | ENSMUSP00000153038 | Sodium-dependent phosphate transport protein 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Plays a role in urate transport in the kidney; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. | Sodium-dependent phosphate transport protein 2A; Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx. | 0.822 |
Slc17a1 | Slc5a8 | ENSMUSP00000006785 | ENSMUSP00000020255 | Sodium-dependent phosphate transport protein 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Plays a role in urate transport in the kidney; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. | Sodium-coupled monocarboxylate transporter 1; Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)- dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D- lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5- aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. M [...] | 0.474 |
Slc22a13 | Slc12a1 | ENSMUSP00000081855 | ENSMUSP00000028630 | Solute carrier family 22 member 13. | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | 0.552 |
Slc22a13 | Slc17a1 | ENSMUSP00000081855 | ENSMUSP00000006785 | Solute carrier family 22 member 13. | Sodium-dependent phosphate transport protein 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Plays a role in urate transport in the kidney; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. | 0.496 |
Slc22a13 | Slc2a7 | ENSMUSP00000081855 | ENSMUSP00000059106 | Solute carrier family 22 member 13. | Solute carrier family 2, facilitated glucose transporter member 7; Probable sugar transporter. Its physiological substrate is subject to discussion. Does not transport galactose, 2-deoxy-d-glucose and xylose; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | 0.529 |
Slc22a13 | Slc34a1 | ENSMUSP00000081855 | ENSMUSP00000153038 | Solute carrier family 22 member 13. | Sodium-dependent phosphate transport protein 2A; Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx. | 0.601 |
Slc22a13 | Slc36a4 | ENSMUSP00000081855 | ENSMUSP00000057355 | Solute carrier family 22 member 13. | Proton-coupled amino acid transporter 4; Functions as a sodium-independent electroneutral transporter for tryptophan, proline and alanine; Belongs to the amino acid/polyamine transporter 2 family. | 0.635 |
Slc22a13 | Slc47a1 | ENSMUSP00000081855 | ENSMUSP00000010267 | Solute carrier family 22 member 13. | Multidrug and toxin extrusion protein 1; Solute transporter for tetraethylammonium (TEA), 1-methyl-4- phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membran [...] | 0.639 |
Slc22a13 | Slc5a8 | ENSMUSP00000081855 | ENSMUSP00000020255 | Solute carrier family 22 member 13. | Sodium-coupled monocarboxylate transporter 1; Acts as an electrogenic sodium (Na(+)) and chloride (Cl-)- dependent sodium-coupled solute transporter, including transport of monocarboxylates (short-chain fatty acids including L-lactate, D- lactate, pyruvate, acetate, propionate, valerate and butyrate), lactate, mocarboxylate drugs (nicotinate, benzoate, salicylate and 5- aminosalicylate) and ketone bodies (beta-D-hydroxybutyrate, acetoacetate and alpha-ketoisocaproate), with a Na(+):substrate stoichiometry of between 4:1 and 2:1. Catalyzes passive carrier mediated diffusion of iodide. M [...] | 0.533 |
Slc22a13 | Slc6a18 | ENSMUSP00000081855 | ENSMUSP00000152525 | Solute carrier family 22 member 13. | Sodium-dependent neutral amino acid transporter B(0)AT3; Functions as a sodium and chloride-dependent neutral amino acid transporter in kidneys. Required CLTRN for cell surface expression and for its amino acid transporter activity. | 0.520 |
Slc22a13 | Tmem174 | ENSMUSP00000081855 | ENSMUSP00000057581 | Solute carrier family 22 member 13. | Transmembrane protein 174. | 0.559 |
Slc22a13 | Xylb | ENSMUSP00000081855 | ENSMUSP00000047254 | Solute carrier family 22 member 13. | Xylulose kinase; Phosphorylates D-xylulose to produce D-xylulose 5-phosphate, a molecule that may play an important role in the regulation of glucose metabolism and lipogenesis. | 0.494 |
Slc2a7 | Slc22a13 | ENSMUSP00000059106 | ENSMUSP00000081855 | Solute carrier family 2, facilitated glucose transporter member 7; Probable sugar transporter. Its physiological substrate is subject to discussion. Does not transport galactose, 2-deoxy-d-glucose and xylose; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. Glucose transporter subfamily. | Solute carrier family 22 member 13. | 0.529 |
Slc34a1 | Slc12a1 | ENSMUSP00000153038 | ENSMUSP00000028630 | Sodium-dependent phosphate transport protein 2A; Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx. | Solute carrier family 12 member 1; Renal sodium, potassium and chloride ion cotransporter that mediates the transepithelial NaCl reabsorption in the thick ascending limb and plays an essential role in the urinary concentration and volume regulation. Electrically silent transporter system. | 0.830 |
Slc34a1 | Slc17a1 | ENSMUSP00000153038 | ENSMUSP00000006785 | Sodium-dependent phosphate transport protein 2A; Involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Probably mediates 70-80% of the apical influx. | Sodium-dependent phosphate transport protein 1; Important for the resorption of phosphate by the kidney. May be involved in actively transporting phosphate into cells via Na(+) cotransport in the renal brush border membrane. Plays a role in urate transport in the kidney; Belongs to the major facilitator superfamily. Sodium/anion cotransporter family. | 0.822 |