node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Arvcf | Comt | ENSMUSP00000087562 | ENSMUSP00000130077 | Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog; Involved in protein-protein interactions at adherens junctions. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | 0.675 |
Arvcf | Dgcr2 | ENSMUSP00000087562 | ENSMUSP00000012152 | Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog; Involved in protein-protein interactions at adherens junctions. | Integral membrane protein DGCR2/IDD; Probably plays a role in neural crest cell migration. May play a role in delivery of extracellular signals. | 0.438 |
Arvcf | Gnb1l | ENSMUSP00000087562 | ENSMUSP00000087544 | Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog; Involved in protein-protein interactions at adherens junctions. | Guanine nucleotide-binding protein subunit beta-like protein 1. | 0.670 |
Arvcf | Gp1bb | ENSMUSP00000087562 | ENSMUSP00000059270 | Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog; Involved in protein-protein interactions at adherens junctions. | Platelet glycoprotein Ib beta chain; Gp-Ib, a surface membrane protein of platelets, participates in the formation of platelet plugs by binding to von Willebrand factor, which is already bound to the subendothelium. | 0.490 |
Arvcf | Prodh | ENSMUSP00000087562 | ENSMUSP00000003620 | Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog; Involved in protein-protein interactions at adherens junctions. | Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate. | 0.497 |
Arvcf | Sept5 | ENSMUSP00000087562 | ENSMUSP00000094750 | Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog; Involved in protein-protein interactions at adherens junctions. | Septin-5; Filament-forming cytoskeletal GTPase (By similarity). Involved in cytokinesis (Potential). May play a role in platelet secretion; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | 0.432 |
Arvcf | Trmt2a | ENSMUSP00000087562 | ENSMUSP00000111304 | Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog; Involved in protein-protein interactions at adherens junctions. | tRNA (uracil-5-)-methyltransferase homolog A. | 0.608 |
Arvcf | Zdhhc8 | ENSMUSP00000087562 | ENSMUSP00000076224 | Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog; Involved in protein-protein interactions at adherens junctions. | Probable palmitoyltransferase ZDHHC8; Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1; Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. | 0.520 |
Comt | Arvcf | ENSMUSP00000130077 | ENSMUSP00000087562 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog; Involved in protein-protein interactions at adherens junctions. | 0.675 |
Comt | Dgcr2 | ENSMUSP00000130077 | ENSMUSP00000012152 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Integral membrane protein DGCR2/IDD; Probably plays a role in neural crest cell migration. May play a role in delivery of extracellular signals. | 0.562 |
Comt | Gnb1l | ENSMUSP00000130077 | ENSMUSP00000087544 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Guanine nucleotide-binding protein subunit beta-like protein 1. | 0.638 |
Comt | Prodh | ENSMUSP00000130077 | ENSMUSP00000003620 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Proline dehydrogenase 1, mitochondrial; Converts proline to delta-1-pyrroline-5-carboxylate. | 0.841 |
Comt | Sept5 | ENSMUSP00000130077 | ENSMUSP00000094750 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Septin-5; Filament-forming cytoskeletal GTPase (By similarity). Involved in cytokinesis (Potential). May play a role in platelet secretion; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. | 0.484 |
Comt | Tbx1 | ENSMUSP00000130077 | ENSMUSP00000156061 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | T-box transcription factor TBX1; Probable transcriptional regulator involved in developmental processes. Is required for normal development of the pharyngeal arch arteries. | 0.403 |
Comt | Trmt2a | ENSMUSP00000130077 | ENSMUSP00000111304 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | tRNA (uracil-5-)-methyltransferase homolog A. | 0.478 |
Comt | Zdhhc8 | ENSMUSP00000130077 | ENSMUSP00000076224 | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | Probable palmitoyltransferase ZDHHC8; Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1; Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. | 0.772 |
Dgcr2 | Arvcf | ENSMUSP00000012152 | ENSMUSP00000087562 | Integral membrane protein DGCR2/IDD; Probably plays a role in neural crest cell migration. May play a role in delivery of extracellular signals. | Armadillo repeat protein deleted in velo-cardio-facial syndrome homolog; Involved in protein-protein interactions at adherens junctions. | 0.438 |
Dgcr2 | Comt | ENSMUSP00000012152 | ENSMUSP00000130077 | Integral membrane protein DGCR2/IDD; Probably plays a role in neural crest cell migration. May play a role in delivery of extracellular signals. | Catechol O-methyltransferase; Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol; Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O-methyltransferase family. | 0.562 |
Dgcr2 | Dgcr8 | ENSMUSP00000012152 | ENSMUSP00000009321 | Integral membrane protein DGCR2/IDD; Probably plays a role in neural crest cell migration. May play a role in delivery of extracellular signals. | Microprocessor complex subunit DGCR8; Component of the microprocessor complex that acts as a RNA- and heme-binding protein that is involved in the initial step of microRNA (miRNA) biogenesis. Component of the microprocessor complex that is required to process primary miRNA transcripts (pri-miRNAs) to release precursor miRNA (pre-miRNA) in the nucleus. Within the microprocessor complex, DGCR8 function as a molecular anchor necessary for the recognition of pri-miRNA at dsRNA- ssRNA junction and directs DROSHA to cleave 11 bp away form the junction to release hairpin-shaped pre-miRNAs tha [...] | 0.433 |
Dgcr2 | Gnb1l | ENSMUSP00000012152 | ENSMUSP00000087544 | Integral membrane protein DGCR2/IDD; Probably plays a role in neural crest cell migration. May play a role in delivery of extracellular signals. | Guanine nucleotide-binding protein subunit beta-like protein 1. | 0.639 |