STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Slc7a14Probable cationic amino acid transporter; May be involved in arginine transport. (771 aa)    
Predicted Functional Partners:
Pcsk2
Neuroendocrine convertase 2; Involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues. Responsible for the release of glucagon from proglucagon in pancreatic A cells (By similarity).
   
 
 0.668
Frrs1l
DOMON domain-containing protein FRRS1L; Important modulator of glutamate signaling pathway.
   
    0.598
Slc3a1
Neutral and basic amino acid transport protein rBAT; Involved in the high-affinity sodium-independent transport of cystine and neutral and dibasic amino acids (system B(0,+)-like activity). May function as an activator of SLC7A9 and be involved in the high-affinity reabsorption of cystine in the kidney proximal tubule.
   
 
 0.534
Slc7a15
Solute carrier family 7 (cationic amino acid transporter, y+ system), member 15.
  
 
0.510
Rp9
Retinitis pigmentosa 9 protein homolog; Is thought to be a target protein for the PIM1 kinase. May play some roles in B-cell proliferation in association with PIM1.
      
 0.492
Rpl22l1
60S ribosomal protein L22-like 1.
   
  
 0.480
Galnt3
Polypeptide N-acetylgalactosaminyltransferase 3; Catalyzes the initial reaction in O-linked oligosaccharide biosynthesis, the transfer of an N-acetyl-D-galactosamine residue to a serine or threonine residue on the protein receptor. Has activity toward HIV envelope glycoprotein gp120, EA2, Muc2 and Muc5. Glycosylates FGF23 (By similarity). Probably glycosylates fibronectin in vivo. May be involved in phosphate homeostasis.
      
 0.462
Rp1l1
Retinitis pigmentosa 1-like 1 protein; Required for the differentiation of photoreceptor cells. Plays a role in the organization of outer segment of rod and cone photoreceptors.
   
  
 0.455
Slc7a12
Solute carrier family 7 (cationic amino acid transporter, y+ system), member 12.
  
 
0.439
Capn9
Calpain-9; Calcium-regulated non-lysosomal thiol-protease.
   
  
 0.438
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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