node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Amtn | Col17a1 | ENSMUSP00000073081 | ENSMUSP00000026045 | Amelotin; Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis. Belongs to the amelotin family. | 120 kDa linear IgA disease antigen homolog; May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. | 0.641 |
Amtn | Dlx3 | ENSMUSP00000073081 | ENSMUSP00000090443 | Amelotin; Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis. Belongs to the amelotin family. | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family. | 0.627 |
Amtn | Enam | ENSMUSP00000073081 | ENSMUSP00000031222 | Amelotin; Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis. Belongs to the amelotin family. | Enamelin; Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation. | 0.977 |
Amtn | Fam83h | ENSMUSP00000073081 | ENSMUSP00000126453 | Amelotin; Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis. Belongs to the amelotin family. | Protein FAM83H; May play a major role in the structural organization and calcification of developing enamel. May play a role in keratin cytoskeleton disassembly by recruiting CSNK1A1 to keratin filaments. Thereby, it may regulate epithelial cell migration. Belongs to the FAM83 family. | 0.702 |
Amtn | Ibsp | ENSMUSP00000073081 | ENSMUSP00000031246 | Amelotin; Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis. Belongs to the amelotin family. | Bone sialoprotein 2; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment (By similarity). | 0.549 |
Col17a1 | Amtn | ENSMUSP00000026045 | ENSMUSP00000073081 | 120 kDa linear IgA disease antigen homolog; May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. | Amelotin; Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis. Belongs to the amelotin family. | 0.641 |
Col17a1 | Dlx3 | ENSMUSP00000026045 | ENSMUSP00000090443 | 120 kDa linear IgA disease antigen homolog; May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family. | 0.606 |
Col17a1 | Enam | ENSMUSP00000026045 | ENSMUSP00000031222 | 120 kDa linear IgA disease antigen homolog; May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. | Enamelin; Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation. | 0.636 |
Col17a1 | Fam83h | ENSMUSP00000026045 | ENSMUSP00000126453 | 120 kDa linear IgA disease antigen homolog; May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. | Protein FAM83H; May play a major role in the structural organization and calcification of developing enamel. May play a role in keratin cytoskeleton disassembly by recruiting CSNK1A1 to keratin filaments. Thereby, it may regulate epithelial cell migration. Belongs to the FAM83 family. | 0.704 |
Dlx3 | Amtn | ENSMUSP00000090443 | ENSMUSP00000073081 | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family. | Amelotin; Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis. Belongs to the amelotin family. | 0.627 |
Dlx3 | Col17a1 | ENSMUSP00000090443 | ENSMUSP00000026045 | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family. | 120 kDa linear IgA disease antigen homolog; May play a role in the integrity of hemidesmosome and the attachment of basal keratinocytes to the underlying basement membrane. | 0.606 |
Dlx3 | Enam | ENSMUSP00000090443 | ENSMUSP00000031222 | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family. | Enamelin; Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation. | 0.709 |
Dlx3 | Fam83h | ENSMUSP00000090443 | ENSMUSP00000126453 | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family. | Protein FAM83H; May play a major role in the structural organization and calcification of developing enamel. May play a role in keratin cytoskeleton disassembly by recruiting CSNK1A1 to keratin filaments. Thereby, it may regulate epithelial cell migration. Belongs to the FAM83 family. | 0.683 |
Dlx3 | Foxn1 | ENSMUSP00000090443 | ENSMUSP00000103929 | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family. | Forkhead box protein N1; Transcriptional regulator which regulates the development, differentiation, and function of thymic epithelial cells (TECs) both in the prenatal and postnatal thymus. Acts as a master regulator of the TECs lineage development and is required from the onset of differentiation in progenitor TECs in the developing fetus to the final differentiation steps through which TECs mature to acquire their full functionality. Regulates, either directly or indirectly the expression of a variety of genes that mediate diverse aspects of thymus development and function, includin [...] | 0.630 |
Dlx3 | Gcm1 | ENSMUSP00000090443 | ENSMUSP00000024104 | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family. | Chorion-specific transcription factor GCMa; Transcription factor that is necessary for placental development. Involved in the control of expression of placental growth factor (PGF) and other placenta-specific genes. Binds to the trophoblast-specific element 2 (TSE2) of the aromatase gene enhancer. Binds to the SYDE1 promoter. Has a central role in mediating the differentiation of trophoblast cells along both the villous and extravillous pathways in placental development (By similarity). | 0.580 |
Dlx3 | Ibsp | ENSMUSP00000090443 | ENSMUSP00000031246 | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family. | Bone sialoprotein 2; Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment (By similarity). | 0.623 |
Dlx3 | Meis1 | ENSMUSP00000090443 | ENSMUSP00000139219 | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family. | Homeobox protein Meis1; Acts as a transcriptional regulator of PAX6. Also acts as a transcriptional activator of PF4 in complex with PBX1 or PBX2. Required for hematopoiesis, megakaryocyte lineage development and vascular patterning. May function as a cofactor for HOXA7 and HOXA9 in the induction of myeloid leukemias; Belongs to the TALE/MEIS homeobox family. | 0.606 |
Dlx3 | Meis2 | ENSMUSP00000090443 | ENSMUSP00000028639 | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family. | Homeobox protein Meis2; Involved in transcriptional regulation. Binds to HOX or PBX proteins to form dimers, or to a DNA-bound dimer of PBX and HOX proteins and thought to have a role in stabilization of the homeoprotein-DNA complex. Isoform Meis2B is required for the activity of a PDX1:PBX1b:MEIS2b complex in pancreatic acinar cells involved in the transcriptional activation of the ELA1 enhancer; the complex binds to the enhancer B element and cooperates with the transcription factor 1 complex (PTF1) bound to the enhancer A element; MEIS2 is not involved in complex DNA-binding. Probab [...] | 0.578 |
Dlx3 | Sp7 | ENSMUSP00000090443 | ENSMUSP00000077596 | Homeobox protein DLX-3; Likely to play a regulatory role in the development of the ventral forebrain. May play a role in craniofacial patterning and morphogenesis; Belongs to the distal-less homeobox family. | Transcription factor Sp7; Transcriptional activator essential for osteoblast differentiation. Binds to SP1 and EKLF consensus sequences and to other G/C-rich sequences. Belongs to the Sp1 C2H2-type zinc-finger protein family. | 0.680 |
Enam | Amtn | ENSMUSP00000031222 | ENSMUSP00000073081 | Enamelin; Involved in the mineralization and structural organization of enamel. Involved in the extension of enamel during the secretory stage of dental enamel formation. | Amelotin; Is a promoter of calcium phosphate mineralization, playing a critical role in the formation of the compact, mineralized, aprismatic enamel surface layer during the maturation stage of amelogenesis. Belongs to the amelotin family. | 0.977 |