node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
6430548M08Rik | Tmem104 | ENSMUSP00000034281 | ENSMUSP00000056805 | Uncharacterized protein KIAA0513. | Transmembrane protein 104. | 0.460 |
6430548M08Rik | Tmem94 | ENSMUSP00000034281 | ENSMUSP00000091440 | Uncharacterized protein KIAA0513. | Transmembrane protein 94. | 0.518 |
Caskin2 | Tmem104 | ENSMUSP00000041328 | ENSMUSP00000056805 | Caskin-2. | Transmembrane protein 104. | 0.405 |
Caskin2 | Tmem161a | ENSMUSP00000041328 | ENSMUSP00000002413 | Caskin-2. | Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity). | 0.520 |
Caskin2 | Tmem94 | ENSMUSP00000041328 | ENSMUSP00000091440 | Caskin-2. | Transmembrane protein 94. | 0.681 |
Cdk5 | Tmem94 | ENSMUSP00000030814 | ENSMUSP00000091440 | Cyclin-dependent-like kinase 5; Proline-directed serine/threonine-protein kinase essential for neuronal cell cycle arrest and differentiation and may be involved in apoptotic cell death in neuronal diseases by triggering abortive cell cycle re-entry. Interacts with D1 and D3-type G1 cyclins. Phosphorylates SRC, NOS3, VIM/vimentin, p35/CDK5R1, MEF2A, SIPA1L1, SH3GLB1, PXN, PAK1, MCAM/MUC18, SEPT5, SYN1, DNM1, AMPH, SYNJ1, CDK16, RAC1, RHOA, CDC42, TONEBP/NFAT5, MAPT/TAU, MAP1B, histone H1, p53/TP53, HDAC1, APEX1, PTK2/FAK1, huntingtin/HTT, ATM, MAP2, NEFH and NEFM. Regulates several neu [...] | Transmembrane protein 94. | 0.564 |
Syt5 | Tmem178 | ENSMUSP00000070322 | ENSMUSP00000025092 | Synaptotagmin-5; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface; Belongs to the synaptotagmin family. | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | 0.413 |
Syt5 | Tmem94 | ENSMUSP00000070322 | ENSMUSP00000091440 | Synaptotagmin-5; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface; Belongs to the synaptotagmin family. | Transmembrane protein 94. | 0.516 |
Tmem104 | 6430548M08Rik | ENSMUSP00000056805 | ENSMUSP00000034281 | Transmembrane protein 104. | Uncharacterized protein KIAA0513. | 0.460 |
Tmem104 | Caskin2 | ENSMUSP00000056805 | ENSMUSP00000041328 | Transmembrane protein 104. | Caskin-2. | 0.405 |
Tmem104 | Tmem94 | ENSMUSP00000056805 | ENSMUSP00000091440 | Transmembrane protein 104. | Transmembrane protein 94. | 0.554 |
Tmem161a | Caskin2 | ENSMUSP00000002413 | ENSMUSP00000041328 | Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity). | Caskin-2. | 0.520 |
Tmem161a | Tmem94 | ENSMUSP00000002413 | ENSMUSP00000091440 | Transmembrane protein 161A; May play a role in protection against oxidative stress. Overexpression leads to reduced levels of oxidant-induced DNA damage and apoptosis (By similarity). | Transmembrane protein 94. | 0.678 |
Tmem178 | Syt5 | ENSMUSP00000025092 | ENSMUSP00000070322 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Synaptotagmin-5; May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface; Belongs to the synaptotagmin family. | 0.413 |
Tmem178 | Tmem47 | ENSMUSP00000025092 | ENSMUSP00000026760 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Transmembrane protein 47; Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin. | 0.562 |
Tmem178 | Tmem88 | ENSMUSP00000025092 | ENSMUSP00000055528 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Transmembrane protein 88; Inhibits the Wnt/beta-catenin signaling pathway. Crucial for heart development and acts downstream of GATA factors in the pre- cardiac mesoderm to specify lineage commitment of cardiomyocyte development (By similarity); Belongs to the TMEM88 family. | 0.571 |
Tmem178 | Tmem94 | ENSMUSP00000025092 | ENSMUSP00000091440 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Transmembrane protein 94. | 0.694 |
Tmem178 | Tmem97 | ENSMUSP00000025092 | ENSMUSP00000099532 | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | Sigma intracellular receptor 2; Intracellular orphan receptor that binds numerous drugs and which is highly expressed in various proliferating cells. Corresponds to the sigma-2 receptor, which is thought to play important role in regulating cell survival, morphology and differentiation. May play a role as a regulator of cellular cholesterol homeostasis. May function as sterol isomerase. May alter the activity of some cytochrome P450 proteins. | 0.524 |
Tmem47 | Tmem178 | ENSMUSP00000026760 | ENSMUSP00000025092 | Transmembrane protein 47; Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin. | Transmembrane protein 178A; Acts as a negative regulator of osteoclast differentiation in basal and inflammatory conditions by regulating TNFSF11-induced Ca (2+) fluxes, thereby controlling the induction of NFATC1. | 0.562 |
Tmem47 | Tmem94 | ENSMUSP00000026760 | ENSMUSP00000091440 | Transmembrane protein 47; Regulates cell junction organization in epithelial cells. May play a role in the transition from adherens junction to tight junction assembly. May regulate F-actin polymerization required for tight junctional localization dynamics and affect the junctional localization of PARD6B. During podocyte differentiation may negatively regulate activity of FYN and subsequently the abundance of nephrin. | Transmembrane protein 94. | 0.537 |