STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Xkr5XK-related protein 5. (676 aa)    
Predicted Functional Partners:
Vwa5b1
Von Willebrand factor A domain-containing protein 5B1.
      
 0.642
Tatdn2
TatD DNase domain-containing 2.
      
 0.555
Catsperg1
Cation channel sperm-associated protein subunit gamma 1; Belongs to the CATSPERG family.
      
 0.489
Marf1
Meiosis regulator and mRNA stability factor 1; Essential regulator of oogenesis required for female meiotic progression to repress transposable elements and preventing their mobilization, which is essential for the germline integrity. Probably acts via some RNA metabolic process, equivalent to the piRNA system in males, which mediates the repression of transposable elements during meiosis by forming complexes composed of RNAs and governs the methylation and subsequent repression of transposons. Also required to protect from DNA double-strand breaks.
      
 0.478
Dusp21
Dual specificity phosphatase 21; Can dephosphorylate single and diphosphorylated synthetic MAPK peptides, with preference for the phosphotyrosine and diphosphorylated forms over phosphothreonine; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily.
   
  
 0.450
Tmem87b
Transmembrane protein 87B; May be involved in retrograde transport from endosomes to the trans-Golgi network (TGN).
      
 0.440
Sdr42e1
Short-chain dehydrogenase/reductase family 42E member 1.
      
 0.431
Nanp
N-acylneuraminate-9-phosphatase; Belongs to the HAD-like hydrolase superfamily. NANP family.
      
 0.410
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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