STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Gpr152Probable G-protein coupled receptor 152; Orphan receptor; Belongs to the G-protein coupled receptor 1 family. (511 aa)    
Predicted Functional Partners:
Ppp1r26
Protein phosphatase 1 regulatory subunit 26; Inhibits phosphatase activity of protein phosphatase 1 (PP1) complexes. May positively regulate cell proliferation.
    
 
 0.664
Rnf227
RING finger protein 227.
    
 
 0.664
Gpr108
Protein GPR108; Belongs to the LU7TM family.
      
 0.648
Cabp4
Calcium-binding protein 4; Involved in normal synaptic function through regulation of Ca(2+) influx and neurotransmitter release in photoreceptor synaptic terminals and in auditory transmission. Modulator of CACNA1D and CACNA1F, suppressing the calcium-dependent inactivation and shifting the activation range to more hyperpolarized voltages.
   
 
 0.645
Gpr171
Probable G-protein coupled receptor 171; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
      
 0.602
Gpr89
Golgi pH regulator; Voltage dependent anion channel required for acidification and functions of the Golgi apparatus that may function in counter-ion conductance.
      
 0.597
Gpr162
Probable G-protein coupled receptor 162; Orphan receptor; Belongs to the G-protein coupled receptor 1 family.
    
 
 0.593
Minar2
Major intrinsically disordered NOTCH2-binding receptor 1-like homolog; Belongs to the MINAR family.
      
 0.578
Ptrh1
Probable peptidyl-tRNA hydrolase.
      
 0.576
1810055G02Rik
Uncharacterized protein C11orf24 homolog.
   
 
 0.571
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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