STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Tmem88bTransmembrane protein 88B. (173 aa)    
Predicted Functional Partners:
Gjc3
Gap junction gamma-3 protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell; Belongs to the connexin family. Gamma-type subfamily.
   
    0.688
Fam189a1
Protein FAM189A1; Belongs to the FAM189 family.
      
 0.671
Tmem179
Transmembrane protein 179.
   
  
 0.663
Dzank1
Double zinc ribbon and ankyrin repeat-containing protein 1.
   
  
 0.660
Fam131b
Protein FAM131B.
   
  
 0.658
Fam171b
Protein FAM171B; Belongs to the FAM171 family.
   
  
 0.634
Lipn
Lipase member N; Plays a highly specific role in the last step of keratinocyte differentiation. May have an essential function in lipid metabolism of the most differentiated epidermal layers (By similarity). Belongs to the AB hydrolase superfamily. Lipase family.
      
 0.618
Tmem145
Transmembrane protein 145.
      
 0.613
Amer3
APC membrane recruitment protein 3; Regulator of the canonical Wnt signaling pathway. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane (By similarity). Belongs to the Amer family.
      
 0.600
Fam81a
Protein FAM81A; Belongs to the FAM81 family.
      
 0.596
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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