node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Defb4 | Lce3a | ENSMUSP00000079808 | ENSMUSP00000066468 | Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells. | Late cornified envelope 3A. | 0.672 |
Defb4 | Lce3b | ENSMUSP00000079808 | ENSMUSP00000046325 | Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells. | Late cornified envelope 3B. | 0.796 |
Defb4 | Lce3c | ENSMUSP00000079808 | ENSMUSP00000050666 | Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells. | Late cornified envelope 3C. | 0.589 |
Defb4 | Lce3e | ENSMUSP00000079808 | ENSMUSP00000096484 | Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells. | Late cornified envelope 3E. | 0.611 |
Defb4 | Lce3f | ENSMUSP00000079808 | ENSMUSP00000088375 | Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells. | Late cornified envelope 3F. | 0.586 |
Krtap21-1 | Lce1l | ENSMUSP00000077524 | ENSMUSP00000057762 | Keratin-associated protein 21-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 21 family. | Late cornified envelope 1L. | 0.616 |
Krtap21-1 | Lce3a | ENSMUSP00000077524 | ENSMUSP00000066468 | Keratin-associated protein 21-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 21 family. | Late cornified envelope 3A. | 0.449 |
Krtap21-1 | Lce3d | ENSMUSP00000077524 | ENSMUSP00000130993 | Keratin-associated protein 21-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 21 family. | Late cornified envelope 3D. | 0.499 |
Krtap21-1 | Lce3e | ENSMUSP00000077524 | ENSMUSP00000096484 | Keratin-associated protein 21-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 21 family. | Late cornified envelope 3E. | 0.555 |
Krtap21-1 | Sprr2d | ENSMUSP00000077524 | ENSMUSP00000039821 | Keratin-associated protein 21-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 21 family. | Small proline-rich protein 2D; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). | 0.403 |
Krtap21-1 | Sprr2e | ENSMUSP00000077524 | ENSMUSP00000064652 | Keratin-associated protein 21-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 21 family. | Small proline-rich protein 2E; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). | 0.513 |
Lce1l | Krtap21-1 | ENSMUSP00000057762 | ENSMUSP00000077524 | Late cornified envelope 1L. | Keratin-associated protein 21-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 21 family. | 0.616 |
Lce1l | Lce3a | ENSMUSP00000057762 | ENSMUSP00000066468 | Late cornified envelope 1L. | Late cornified envelope 3A. | 0.488 |
Lce1l | Lce3d | ENSMUSP00000057762 | ENSMUSP00000130993 | Late cornified envelope 1L. | Late cornified envelope 3D. | 0.521 |
Lce1l | Lce3e | ENSMUSP00000057762 | ENSMUSP00000096484 | Late cornified envelope 1L. | Late cornified envelope 3E. | 0.579 |
Lce1l | Sprr2d | ENSMUSP00000057762 | ENSMUSP00000039821 | Late cornified envelope 1L. | Small proline-rich protein 2D; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). | 0.415 |
Lce1l | Sprr2e | ENSMUSP00000057762 | ENSMUSP00000064652 | Late cornified envelope 1L. | Small proline-rich protein 2E; Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase. All that results in the formation of an insoluble envelope beneath the plasma membrane (By similarity). | 0.497 |
Lce3a | Defb4 | ENSMUSP00000066468 | ENSMUSP00000079808 | Late cornified envelope 3A. | Beta-defensin 4; Exhibits antimicrobial activity against Gram-negative bacteria and Gram-positive bacteria. May act as a ligand for C-C chemokine receptor CCR6. Can bind to mouse (but not human) CCR6 and induce chemotactic activity of CCR6-expressing cells. | 0.672 |
Lce3a | Krtap21-1 | ENSMUSP00000066468 | ENSMUSP00000077524 | Late cornified envelope 3A. | Keratin-associated protein 21-1; In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin- associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins; Belongs to the KRTAP type 21 family. | 0.449 |
Lce3a | Lce1l | ENSMUSP00000066468 | ENSMUSP00000057762 | Late cornified envelope 3A. | Late cornified envelope 1L. | 0.488 |