STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Abca8aATP-binding cassette sub-family A member 8-A; ATP-dependent lipophilic drug transporter. (1619 aa)    
Predicted Functional Partners:
Abca8b
ATP-binding cassette sub-family A member 8-B; ATP-dependent lipophilic drug transporter; Belongs to the ABC transporter superfamily. ABCA family.
  
0.962
Abca13
ATP-binding cassette sub-family A member 13.
    
 
0.659
Abca6
ATP-binding cassette sub-family A member 6; Probable transporter which may play a role in macrophage lipid homeostasis.
  
 
0.633
Prr11
Proline-rich protein 11; Plays a critical role in cell cycle progression.
    
 
 0.550
Slc17a4
Probable small intestine urate exporter; Acts as a membrane potential-dependent organic anion transporter, the transport requires a low concentration of chloride ions. May be involved in urate extrusion from the intestinal duct. May recognize hydrophilic anionic drugs such as aspirin, salicylate, and ibuprofen as substrates. Able to actively transport inorganic phosphate into cells via Na(+) cotransport (in vitro) (By similarity). Belongs to the major facilitator superfamily. Sodium/anion cotransporter family.
   
  
 0.528
Abca5
ATP-binding cassette sub-family A member 5; May play a role in the processing of autolysosomes.
  
 
0.490
Sult5a1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
   
  
 0.405
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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