node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Aadacl3 | Urad | ENSMUSP00000101375 | ENSMUSP00000098000 | Arylacetamide deacetylase-like 3. | 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; Catalyzes the stereoselective decarboxylation of 2-oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin. | 0.489 |
Agxt | Ces1c | ENSMUSP00000027491 | ENSMUSP00000034189 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Carboxylesterase 1C; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant; Belongs to the type-B carboxylesterase/lipase family. | 0.930 |
Agxt | Cyp2c67 | ENSMUSP00000027491 | ENSMUSP00000065796 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Cytochrome P450, family 2, subfamily c, polypeptide 67; Belongs to the cytochrome P450 family. | 0.812 |
Agxt | Cyp3a59 | ENSMUSP00000027491 | ENSMUSP00000049494 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Cytochrome P450, family 3, subfamily a, polypeptide 59. | 0.735 |
Agxt | Gulo | ENSMUSP00000027491 | ENSMUSP00000060912 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | L-gulonolactone oxidase; Oxidizes L-gulono-1,4-lactone to hydrogen peroxide and L- xylo-hexulonolactone which spontaneously isomerizes to L-ascorbate. Belongs to the oxygen-dependent FAD-linked oxidoreductase family. | 0.469 |
Agxt | Uox | ENSMUSP00000027491 | ENSMUSP00000029837 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. | 0.716 |
Agxt | Urad | ENSMUSP00000027491 | ENSMUSP00000098000 | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; Catalyzes the stereoselective decarboxylation of 2-oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin. | 0.509 |
Ccdc59 | Urad | ENSMUSP00000020049 | ENSMUSP00000098000 | Thyroid transcription factor 1-associated protein 26; Component of the transcription complexes of the pulmonary surfactant-associated protein-B (SFTPB) and -C (SFTPC). Enhances homeobox protein Nkx-2.1-activated SFTPB and SFTPC promoter activities (By similarity); Belongs to the TAP26 family. | 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; Catalyzes the stereoselective decarboxylation of 2-oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin. | 0.503 |
Ces1c | Agxt | ENSMUSP00000034189 | ENSMUSP00000027491 | Carboxylesterase 1C; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant; Belongs to the type-B carboxylesterase/lipase family. | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | 0.930 |
Ces1c | Cyp2c67 | ENSMUSP00000034189 | ENSMUSP00000065796 | Carboxylesterase 1C; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant; Belongs to the type-B carboxylesterase/lipase family. | Cytochrome P450, family 2, subfamily c, polypeptide 67; Belongs to the cytochrome P450 family. | 0.826 |
Ces1c | Cyp3a59 | ENSMUSP00000034189 | ENSMUSP00000049494 | Carboxylesterase 1C; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant; Belongs to the type-B carboxylesterase/lipase family. | Cytochrome P450, family 3, subfamily a, polypeptide 59. | 0.792 |
Ces1c | Uox | ENSMUSP00000034189 | ENSMUSP00000029837 | Carboxylesterase 1C; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant; Belongs to the type-B carboxylesterase/lipase family. | Uricase; Catalyzes the oxidation of uric acid to 5-hydroxyisourate, which is further processed to form (S)-allantoin. | 0.520 |
Ces1c | Urad | ENSMUSP00000034189 | ENSMUSP00000098000 | Carboxylesterase 1C; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant; Belongs to the type-B carboxylesterase/lipase family. | 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; Catalyzes the stereoselective decarboxylation of 2-oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin. | 0.465 |
Cyp2c67 | Agxt | ENSMUSP00000065796 | ENSMUSP00000027491 | Cytochrome P450, family 2, subfamily c, polypeptide 67; Belongs to the cytochrome P450 family. | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | 0.812 |
Cyp2c67 | Ces1c | ENSMUSP00000065796 | ENSMUSP00000034189 | Cytochrome P450, family 2, subfamily c, polypeptide 67; Belongs to the cytochrome P450 family. | Carboxylesterase 1C; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant; Belongs to the type-B carboxylesterase/lipase family. | 0.826 |
Cyp2c67 | Cyp3a59 | ENSMUSP00000065796 | ENSMUSP00000049494 | Cytochrome P450, family 2, subfamily c, polypeptide 67; Belongs to the cytochrome P450 family. | Cytochrome P450, family 3, subfamily a, polypeptide 59. | 0.852 |
Cyp2c67 | Urad | ENSMUSP00000065796 | ENSMUSP00000098000 | Cytochrome P450, family 2, subfamily c, polypeptide 67; Belongs to the cytochrome P450 family. | 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase; Catalyzes the stereoselective decarboxylation of 2-oxo-4- hydroxy-4-carboxy-5-ureidoimidazoline (OHCU) to (S)-allantoin. | 0.685 |
Cyp3a59 | Agxt | ENSMUSP00000049494 | ENSMUSP00000027491 | Cytochrome P450, family 3, subfamily a, polypeptide 59. | Serine--pyruvate aminotransferase, mitochondrial; Dual metabolic roles of gluconeogenesis (in the mitochondria) and glyoxylate detoxification (in the peroxisomes). | 0.735 |
Cyp3a59 | Ces1c | ENSMUSP00000049494 | ENSMUSP00000034189 | Cytochrome P450, family 3, subfamily a, polypeptide 59. | Carboxylesterase 1C; Involved in the detoxification of xenobiotics and in the activation of ester and amide prodrugs. Involved in the extracellular metabolism of lung surfactant; Belongs to the type-B carboxylesterase/lipase family. | 0.792 |
Cyp3a59 | Cyp2c67 | ENSMUSP00000049494 | ENSMUSP00000065796 | Cytochrome P450, family 3, subfamily a, polypeptide 59. | Cytochrome P450, family 2, subfamily c, polypeptide 67; Belongs to the cytochrome P450 family. | 0.852 |