STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Wfdc3WAP four-disulfide core domain protein 3. (130 aa)    
Predicted Functional Partners:
Wfdc13
WAP four-disulfide core domain protein 13; Putative acid-stable proteinase inhibitor.
   
 
 0.671
Spata25
Spermatogenesis-associated protein 25; May play a role in spermatogenesis; Belongs to the SPATA25 family.
      
 0.630
Trim43c
Tripartite motif-containing protein 43C.
   
  
 0.609
Wfdc6b
WAP four-disulfide core domain protein 6B.
      
 0.607
Mbd3l2
Methyl-CpG-binding domain protein 3-like 2.
   
  
 0.607
Pramef6
PRAME family member 6.
      
 0.603
Rhov
Rho-related GTP-binding protein RhoV; Plays a role in the control of the actin cytoskeleton via activation of the JNK pathway; Belongs to the small GTPase superfamily. Rho family.
   
    0.580
Wfdc10
WAP four-disulfide core domain 10.
   
  
 0.574
Trim36
E3 ubiquitin-protein ligase Trim36; E3 ubiquitin-protein ligase which mediates ubiquitination and subsequent proteasomal degradation of target proteins. Involved in chromosome segregation and cell cycle regulation. May play a role in the acrosome reaction and fertilization ; Belongs to the TRIM/RBCC family.
      
 0.555
Sbpl
Spermine-binding protein-like.
      
 0.552
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.