STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Rpl23a60S ribosomal protein L23a; Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. Binds a specific region on the 26S rRNA (By similarity). May promote p53/TP53 degradation possibly through the stimulation of MDM2-mediated TP53 polyubiquitination (By similarity); Belongs to the universal ribosomal protein uL23 family. (156 aa)    
Predicted Functional Partners:
Rpl13
60S ribosomal protein L13; Belongs to the eukaryotic ribosomal protein eL13 family.
   
 
 0.999
Rps11
40S ribosomal protein S11.
  
 
 0.999
Rps18
40S ribosomal protein S18; Located at the top of the head of the 40S subunit, it contacts several helices of the 18S rRNA.
  
 
 0.999
Rpl19
60S ribosomal protein L19.
  
 
 0.999
Rack1
Receptor of activated protein C kinase 1, N-terminally processed; Scaffolding protein involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Component of the 40S ribosomal subunit involved in translational repression. Involved in the initiation of the ribosome quality control (RQC), a pathway that takes place when a ribosome has stalled during translation, by promoting ubiquitination of a subset of 40S ribosomal subunits (By similarity). Binds to and stabilizes a [...]
   
 
 0.999
Mrpl36
39S ribosomal protein L36, mitochondrial; Belongs to the bacterial ribosomal protein bL36 family.
  
 
 0.999
Rpl24
60S ribosomal protein L24; Belongs to the eukaryotic ribosomal protein eL24 family.
   
 
 0.999
Mrpl27
39S ribosomal protein L27, mitochondrial; Belongs to the bacterial ribosomal protein bL27 family.
   
 
 0.999
Mrpl21
39S ribosomal protein L21, mitochondrial.
   
 
 0.999
Rps26
40S ribosomal protein S26; Belongs to the eukaryotic ribosomal protein eS26 family.
   
 
 0.999
Your Current Organism:
Mus musculus
NCBI taxonomy Id: 10090
Other names: LK3 transgenic mice, M. musculus, Mus sp. 129SV, house mouse, mouse, nude mice, transgenic mice
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